{"id":"W1968419884","doi":"10.1021/bi901086v","title":"Cell Membrane Expression of Cardiac Sodium Channel Na<sub>v</sub>1.5 Is Modulated by α-Actinin-2 Interaction","year":2009,"lang":"en","type":"article","venue":"Biochemistry","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre hospitalier de l'Université Laval; Université Laval","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Canadian Institutes of Health Research","keywords":"Chemistry; Cardiac cell; Membrane; Cell biology; Cell membrane; Sodium channel; Biophysics; Sodium; Cell; Expression (computer science); Biochemistry; Biology; Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009529203,0.0002140408,0.0001888389,0.00003677581,0.00006902721,0.00001682606,0.0001184554,0.0003618064,0.00002597833],"category_scores_gemma":[0.0000304076,0.0002211725,0.0001634321,0.0001073316,0.00004001558,0.000009572293,0.00004006782,0.0001092819,0.00001082616],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002889978,"about_ca_system_score_gemma":0.00004013386,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004465775,"about_ca_topic_score_gemma":8.212627e-8,"domain_scores_codex":[0.9988689,0.00003087222,0.000282876,0.0004134011,0.0001929608,0.0002109275],"domain_scores_gemma":[0.999179,0.000006482444,0.0002088648,0.0003514026,0.0001501631,0.0001040945],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001982312,0.0001186871,0.00002241374,0.00003942891,0.00001527057,2.950944e-7,0.00003876133,0.00003651787,0.9681259,2.238417e-7,0.03008031,0.001323995],"study_design_scores_gemma":[0.0003971468,0.0001281738,0.00009929497,0.00003136429,0.00001642026,0.0000040989,0.0001422154,0.0004712977,0.994976,0.000005827952,0.003499649,0.0002284938],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969584,0.0005401111,0.0004348916,0.0001503861,0.0004955137,0.0001232899,0.00006259024,0.00003124138,0.001203565],"genre_scores_gemma":[0.9974416,0.0002262313,0.00004544302,0.0001877941,0.0004030411,0.000009619055,0.0008503742,0.00002135922,0.0008144958],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02685015,"threshold_uncertainty_score":0.9019153,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007384088247930368,"score_gpt":0.2216130172670264,"score_spread":0.2142289290190961,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}