{"id":"W1968430623","doi":"10.3747/co.v17is1.616","title":"Efficacy of the Monoclonal Antibody EGFR Inhibitors for the Treatment of Metastatic Colorectal Cancer","year":2010,"lang":"en","type":"article","venue":"Current Oncology","topic":"Colorectal Cancer Treatments and Studies","field":"Medicine","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"CancerCare Manitoba","funders":"","keywords":"Panitumumab; Cetuximab; Medicine; Irinotecan; KRAS; Colorectal cancer; Monoclonal antibody; Oncology; Epidermal growth factor receptor; Internal medicine; EGFR inhibitors; Cancer research; Cancer; Antibody; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001061161,0.0002597346,0.0006574989,0.0003754477,0.0001619456,0.0003529435,0.0002239412,0.0003002368,0.001787261],"category_scores_gemma":[0.0009551311,0.00008432203,0.0004678932,0.0002398366,0.0001815077,0.0002694388,0.0001154588,0.0007703431,0.0003063952],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005630774,"about_ca_system_score_gemma":0.0003450209,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000670654,"about_ca_topic_score_gemma":0.002167358,"domain_scores_codex":[0.9997508,0.00009168035,0.00002135666,0.0000192805,0.00009318194,0.00002376968],"domain_scores_gemma":[0.9997076,0.0001056957,0.00008212538,0.00001233386,0.00004824496,0.00004389998],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.005292411,0.001069575,0.003790939,0.002119789,0.000407823,0.0002310278,0.00006340486,0.0008214857,0.03561285,0.00140338,0.007021653,0.9421657],"study_design_scores_gemma":[0.005715747,0.1030139,0.1529977,0.002031035,0.002951741,0.008873667,0.0001699376,0.001902779,0.1125753,0.002340935,0.6073303,0.00009699028],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.1184117,0.8525538,0.0008771743,0.003023567,0.0004548365,0.00009715219,0.0001893892,0.00004993031,0.02434241],"genre_scores_gemma":[0.6572068,0.3305958,0.001380484,0.001276842,0.0009192971,0.00006214776,0.000317239,0.00002321825,0.008218171],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.001787261,"threshold_uncertainty_score":0.005979002,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09151282820670831,"score_gpt":0.4478608466085474,"score_spread":0.3563480184018391,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}