{"id":"W1968437765","doi":"10.2353/ajpath.2008.080358","title":"Differential Roles of JNK in ConA/GalN and ConA-Induced Liver Injury in Mice","year":2008,"lang":"en","type":"article","venue":"American Journal Of Pathology","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institutes of Health; University of Toronto; National Cancer Institute; American Liver Foundation","keywords":"Programmed cell death; Apoptosis; Necrosis; Biology; Liver injury; Tumor necrosis factor alpha; Caspase; Hepatocyte; Death domain; Poly ADP ribose polymerase; Cell biology; Immunology; Cancer research; Endocrinology; Biochemistry; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000109092,0.00007902113,0.0002556009,0.0001165963,0.00001353061,0.000001647976,0.00007167971,0.00007490654,0.000009838174],"category_scores_gemma":[0.00002706378,0.00006872934,0.00004608391,0.00006761973,0.0002005036,0.000003585655,0.00003868986,0.0001023666,3.059578e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009583003,"about_ca_system_score_gemma":0.00005704797,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003254383,"about_ca_topic_score_gemma":0.0000429777,"domain_scores_codex":[0.9992952,0.0001146994,0.0002959153,0.0001162159,0.00006327211,0.0001146758],"domain_scores_gemma":[0.999553,0.0000134453,0.0002696075,0.00006862608,0.00005697552,0.00003839085],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002231215,0.00005411393,0.01033871,0.000004013712,0.00001008826,0.0001513808,0.0002810282,0.00001036007,0.9678174,0.00004326146,0.000009990385,0.0210565],"study_design_scores_gemma":[0.002232615,0.004141288,0.4396519,0.00004674682,0.00002654834,0.002594163,0.0006091108,0.0001388578,0.5497715,0.0001801665,0.0003679723,0.000239082],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990361,0.0003655421,0.0004043575,0.00004494269,0.00007148302,0.00004249212,0.000003220168,6.862198e-7,0.00003118049],"genre_scores_gemma":[0.9982227,0.001139868,0.000481327,0.00006398112,0.0000644981,9.436761e-7,0.000003905887,0.00000707075,0.00001570761],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4293132,"threshold_uncertainty_score":0.2802701,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007425599176943922,"score_gpt":0.2321272208342865,"score_spread":0.2247016216573426,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}