{"id":"W1968484794","doi":"10.1074/jbc.m113.517581","title":"Vitamin D Inhibits COX-2 Expression and Inflammatory Response by Targeting Thioesterase Superfamily Member 4","year":2014,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Vitamin D Research Studies","field":"Medicine","cited_by":152,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Directorate for Biological Sciences; Chinese Academy of Sciences; Collaborative Innovation Center for Cardiovascular Disease Translational Medicine; National Natural Science Foundation of China","keywords":"Proinflammatory cytokine; Inflammation; Protein kinase B; Calcitriol receptor; Gene knockdown; Chemistry; Vitamin; Phosphorylation; Endocrinology; Biology; Vitamin D and neurology; Internal medicine; Pharmacology; Medicine; Immunology; Biochemistry; Apoptosis","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001645979,0.0001700247,0.0004147649,0.00003316819,0.00009580678,0.00002190899,0.0001105932,0.000222851,0.00007486561],"category_scores_gemma":[0.005000801,0.00009882105,0.00009623275,0.00006612659,0.0002609089,0.00007416211,0.0001733057,0.0005937888,0.000004211369],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005687277,"about_ca_system_score_gemma":0.00004910373,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":3.775044e-7,"about_ca_topic_score_gemma":1.921915e-8,"domain_scores_codex":[0.9985119,0.0002023187,0.0004749427,0.0001949651,0.0003439169,0.0002719232],"domain_scores_gemma":[0.9984173,0.0007141333,0.0002066345,0.00013294,0.0002212575,0.00030776],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009504456,0.00008865843,0.03963643,0.0001079706,0.00002843641,0.00009709752,0.00007680091,3.565495e-7,0.9487742,3.218066e-7,0.009799339,0.0004399875],"study_design_scores_gemma":[0.001849429,0.000531081,0.04128165,0.0003859347,0.00001637637,0.0003368732,0.0004071351,0.00001742259,0.9456986,0.0000205294,0.00931891,0.0001360847],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970629,0.001393733,0.00003587511,0.0009040599,0.00003636954,0.00007082391,0.000005162079,0.00001714641,0.0004739657],"genre_scores_gemma":[0.9981855,0.0003786018,0.0005331857,0.0002530766,0.0002577627,0.000003585244,0.000005235579,0.00001053096,0.0003725429],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003354822,"threshold_uncertainty_score":0.5986787,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02001514762552131,"score_gpt":0.2858973283160479,"score_spread":0.2658821806905265,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}