{"id":"W1968514469","doi":"10.1073/pnas.1202070109","title":"Histone H3K4 demethylation is negatively regulated by histone H3 acetylation in <i>Saccharomyces cerevisiae</i>","year":2012,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; Child and Family Research Institute; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"H3K4me3; Histone H3; Histone methylation; Demethylase; Histone methyltransferase; Histone; Histone H2A; Biology; Histone code; Molecular biology; Biochemistry; Chemistry; Cell biology; Promoter; Gene expression; Nucleosome; DNA methylation; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007126927,0.0003343755,0.0002151793,0.0001374794,0.0002433403,0.000407104,0.0002431693,0.0001316571,0.0007755137],"category_scores_gemma":[0.00007351307,0.0002033075,0.0002582629,0.0001749124,0.000202675,0.00008948065,0.0003227296,0.0002990168,0.0003547511],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005712185,"about_ca_system_score_gemma":0.000265021,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004535094,"about_ca_topic_score_gemma":0.006819377,"domain_scores_codex":[0.9999162,0.000006136003,0.000009235033,0.00002768538,0.00002501994,0.00001576177],"domain_scores_gemma":[0.999927,0.000006241954,0.00002124234,0.000009971742,0.00001265493,0.00002287002],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005947215,0.000005374211,0.0008703189,0.00002099018,0.000004456211,0.00005000889,0.000007609198,0.00004615734,0.9980975,0.00004641681,0.00004960628,0.0007420735],"study_design_scores_gemma":[0.000009570665,0.00003863866,0.02724328,0.000004177303,0.00001593114,0.000150871,0.0000311479,0.001021788,0.9683469,0.00005003224,0.003080546,0.000007119174],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924169,0.001612011,0.002805518,0.00009503506,0.00004269959,0.00001159356,0.001195359,0.0001476557,0.001673323],"genre_scores_gemma":[0.9941571,0.0005803306,0.001243034,0.00006338669,0.0000047632,0.00001049054,0.001147443,0.00003429851,0.002759117],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004535094,"threshold_uncertainty_score":0.009017348,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03484388224344204,"score_gpt":0.3426007766090489,"score_spread":0.3077568943656069,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}