{"id":"W1968530727","doi":"10.1006/abio.2000.4884","title":"Synthesis and Characterization of an Immobilized Phenylethanolamine N-Methyltransferase Liquid Chromatographic Stationary Phase","year":2001,"lang":"en","type":"article","venue":"Analytical Biochemistry","topic":"Synthesis and Biological Activity","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Phenylethanolamine; Phenylethanolamine N-methyltransferase; Chemistry; Glutaraldehyde; Chromatography; Covalent bond; Methyltransferase; Enzyme; Epinephrine; High-performance liquid chromatography; Immobilized enzyme; Biochemistry; Organic chemistry; DNA; Methylation; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003075855,0.0004860439,0.0004095101,0.0004382613,0.0003244349,0.0004769473,0.0005685586,0.0003927959,0.001297954],"category_scores_gemma":[0.0005549108,0.0003239373,0.0003858504,0.0005137699,0.0002355249,0.0003055569,0.0002357606,0.0009564505,0.00181234],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004907458,"about_ca_system_score_gemma":0.0009481807,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001868253,"about_ca_topic_score_gemma":0.002083684,"domain_scores_codex":[0.9997883,0.00001989104,0.00001987225,0.00004238346,0.00009017503,0.00003922615],"domain_scores_gemma":[0.9995976,0.0001363553,0.00005223058,0.00004881145,0.0000986961,0.00006633503],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002909659,0.00002765115,0.0000387337,0.00001369749,0.000002697566,0.00002184511,0.000004689753,0.0000393413,0.9980845,0.00004718966,0.00002232145,0.001668016],"study_design_scores_gemma":[0.000006544908,0.00006427889,0.0004341183,0.000001798321,0.000006997942,0.00004172396,0.000004441012,0.0002907251,0.9981989,0.00002913275,0.0009189894,0.00000235002],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6844167,0.002533436,0.3014673,0.0007419052,0.0001741108,0.0006553456,0.003106877,0.001532213,0.00537215],"genre_scores_gemma":[0.7315581,0.002897435,0.2342117,0.0004915377,0.0001122297,0.0005607207,0.01115305,0.0005172335,0.01849794],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001868253,"threshold_uncertainty_score":0.004342079,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01083924027865047,"score_gpt":0.2673348300106321,"score_spread":0.2564955897319816,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}