{"id":"W1968530727","doi":"10.1006/abio.2000.4884","title":"Synthesis and Characterization of an Immobilized Phenylethanolamine N-Methyltransferase Liquid Chromatographic Stationary Phase","year":2001,"lang":"en","type":"article","venue":"Analytical Biochemistry","topic":"Synthesis and Biological Activity","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Phenylethanolamine; Phenylethanolamine N-methyltransferase; Chemistry; Glutaraldehyde; Chromatography; Covalent bond; Methyltransferase; Enzyme; Epinephrine; High-performance liquid chromatography; Immobilized enzyme; Biochemistry; Organic chemistry; DNA; Methylation; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002050231,0.0001871536,0.0002650575,0.00003978363,0.00005329093,0.00001694905,0.0001339107,0.0002364243,0.0001323584],"category_scores_gemma":[0.0002230071,0.0001560691,0.0001111175,0.0001674143,0.0002577528,0.000009937982,0.00004490285,0.00007209605,0.00000123162],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006180348,"about_ca_system_score_gemma":0.00003375566,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007982494,"about_ca_topic_score_gemma":8.623378e-7,"domain_scores_codex":[0.9988558,0.00007563411,0.0002867133,0.0004468484,0.0001327995,0.0002021465],"domain_scores_gemma":[0.9993175,0.00006277145,0.00008244685,0.0002972211,0.00008466628,0.0001554451],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007519495,0.0006907007,0.00109307,0.00003624254,0.00006986147,0.000006453861,0.000004261301,1.938411e-7,0.9890499,0.00001623508,0.00000450582,0.008276698],"study_design_scores_gemma":[0.0005334759,0.0006373334,0.003345642,0.00001857239,0.00006146274,0.00002973617,0.00002469162,0.0002438516,0.9942972,0.00001659144,0.0005896145,0.0002018346],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988061,0.000122959,0.0004623279,0.0001450907,0.00001365843,0.0001024626,0.0001251463,0.00001689785,0.0002054196],"genre_scores_gemma":[0.9985379,0.0004971976,0.0001965719,0.00009447805,0.0001115856,0.00002268646,0.0004751678,0.0000133656,0.00005105091],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008074864,"threshold_uncertainty_score":0.6364313,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01083924027865047,"score_gpt":0.2673348300106321,"score_spread":0.2564955897319816,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}