{"id":"W1968567114","doi":"10.1016/j.ajpath.2014.11.027","title":"Nonclassical Resident Macrophages Are Important Determinants in the Development of Myocardial Fibrosis","year":2015,"lang":"en","type":"article","venue":"American Journal Of Pathology","topic":"Cardiac Fibrosis and Remodeling","field":"Medicine","cited_by":77,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research; Killam Trusts; Nova Scotia Health Research Foundation","keywords":"Macrophage; Angiotensin II; Fibrosis; Integrin alpha M; Flow cytometry; CX3CR1; Sirius Red; Fibroblast; Chemistry; Myocardial fibrosis; Phenotype; Medicine; Cancer research; Immunology; Pathology; In vitro; Internal medicine; Inflammation; Receptor; Chemokine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001304012,0.000113418,0.0007300481,0.0001620864,0.00002588471,0.000006777346,0.0001349258,0.00004972886,0.000003043463],"category_scores_gemma":[0.0002027089,0.00006632321,0.0002049068,0.0002043351,0.0002513641,0.00003465511,0.00004632755,0.0002634897,0.000001991669],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007692376,"about_ca_system_score_gemma":0.0003904097,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001210705,"about_ca_topic_score_gemma":0.00001392804,"domain_scores_codex":[0.9981765,0.0002153121,0.0008783748,0.0001221179,0.0003985933,0.0002090898],"domain_scores_gemma":[0.9986596,0.00009497008,0.0007524677,0.0001760885,0.0001911264,0.0001257995],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001714829,0.0003314243,0.8133032,0.00005094785,0.0001468378,0.003917143,0.02052126,0.00009661577,0.05368774,0.0000159007,0.0009917505,0.1052223],"study_design_scores_gemma":[0.001539184,0.001865754,0.9693605,0.0002622704,0.0001342616,0.005602753,0.01364437,0.00006089333,0.006595878,0.00005046638,0.0007597433,0.0001238917],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984381,0.0004289133,0.0002561658,0.0004892605,0.0001925878,0.00008319468,0.000002973827,0.000002435761,0.000106416],"genre_scores_gemma":[0.9921224,0.00009069025,0.007384588,0.0001839787,0.0001955802,0.000002319333,6.118324e-7,0.0000115327,0.000008265898],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1560573,"threshold_uncertainty_score":0.2704582,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02761629296060194,"score_gpt":0.3108083442013728,"score_spread":0.2831920512407708,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}