{"id":"W1968592009","doi":"10.1016/j.jcf.2011.10.003","title":"Effect of dornase alfa on inflammation and lung function: Potential role in the early treatment of cystic fibrosis","year":2011,"lang":"en","type":"article","venue":"Journal of Cystic Fibrosis","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":77,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute","keywords":"Cystic fibrosis; Medicine; Exacerbation; Observational study; Lung function; Internal medicine; Lung; Inflammation; Placebo; Intensive care medicine; Gastroenterology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008818238,0.0002371545,0.0007127696,0.0004473034,0.0000585,0.00002464991,0.0001503295,0.0001017692,0.00009305301],"category_scores_gemma":[0.0006748452,0.000140642,0.0002493284,0.0003612734,0.0001762755,0.0002352424,0.00002668024,0.0002161272,0.00000492432],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000145406,"about_ca_system_score_gemma":0.00009946543,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000140814,"about_ca_topic_score_gemma":0.000006768629,"domain_scores_codex":[0.9974056,0.000393258,0.0008955121,0.0001845216,0.0008501133,0.0002709482],"domain_scores_gemma":[0.997515,0.001165644,0.0006143258,0.0003120282,0.0002394328,0.0001535398],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.06061939,0.001040658,0.03004773,0.001856222,0.0006499778,0.0002421762,0.004358451,0.0004827178,0.8189715,0.0001497304,0.0002164705,0.08136504],"study_design_scores_gemma":[0.0114795,0.08230858,0.643402,0.00232149,0.001789893,0.0005391935,0.0005565229,0.001308096,0.2551158,0.0006133791,0.0003194665,0.0002460955],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958894,0.002231455,0.0007692894,0.0001055931,0.0001515609,0.0005785591,0.00002367586,0.000006830696,0.000243661],"genre_scores_gemma":[0.9967683,0.0001273619,0.002816015,0.00000753688,0.000199154,0.00002120821,0.00000628398,0.00002067446,0.00003346153],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6133543,"threshold_uncertainty_score":0.5735213,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00918984070391594,"score_gpt":0.2667864532162647,"score_spread":0.2575966125123488,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}