{"id":"W1968663928","doi":"10.1182/blood-2002-10-3093","title":"Cell type–specific regulation of von Willebrand factor expression by the E4BP4 transcriptional repressor","year":2004,"lang":"en","type":"article","venue":"Blood","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Chromatin immunoprecipitation; Molecular biology; Repressor; Biology; Transcription factor; Promoter; Transcription (linguistics); Transcriptional regulation; Chromatin; Cell biology; Gene expression; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009763661,0.0002727895,0.0002023742,0.000275271,0.0001243242,0.0002942805,0.0001603621,0.0001746719,0.002402146],"category_scores_gemma":[0.0001875104,0.000160512,0.000173957,0.0001291089,0.0002533435,0.0001440196,0.0002406975,0.000300688,0.0008235878],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001916609,"about_ca_system_score_gemma":0.0001265257,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004948775,"about_ca_topic_score_gemma":0.000502881,"domain_scores_codex":[0.9998639,0.00002449795,0.000008699315,0.00004051041,0.00002904056,0.00003328833],"domain_scores_gemma":[0.9998906,0.00003212581,0.00002246309,0.00002039616,0.0000143013,0.00002013436],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003833506,0.000008782271,0.0002139725,0.000005444109,0.000001269722,0.0000190366,0.000006353097,0.0000118657,0.9991335,0.00005376085,0.0000136974,0.0004938478],"study_design_scores_gemma":[0.00001192281,0.00007888666,0.01760657,0.000002817323,0.000006471818,0.0003018318,0.00002681494,0.0007456915,0.9792676,0.0001007387,0.001845221,0.000005480302],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991477,0.00120326,0.004988155,0.00005480219,0.00002281839,0.00001850453,0.0003681948,0.0001011453,0.001766111],"genre_scores_gemma":[0.9909357,0.0004606373,0.002468778,0.000024496,0.000009979777,0.00002805595,0.0007447654,0.00003691481,0.005290653],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002402146,"threshold_uncertainty_score":0.008036017,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01393763625896525,"score_gpt":0.2268180910794466,"score_spread":0.2128804548204813,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}