{"id":"W1968763049","doi":"10.1517/14712598.1.3.359","title":"Anticytokine gene therapy of autoimmune diseases","year":2001,"lang":"en","type":"review","venue":"Expert Opinion on Biological Therapy","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute on Aging; National Institutes of Health","keywords":"Genetic enhancement; Immunology; Biology; Naked DNA; DNA vaccination; Autoimmunity; Immune system; Cytokine; Medicine; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002992178,0.000470067,0.0003564488,0.0004959693,0.0001292215,0.0004111585,0.0002726686,0.000514316,0.001808776],"category_scores_gemma":[0.0002060025,0.0001002441,0.0002749586,0.0003213403,0.0003692885,0.0002752237,0.0003550068,0.0007826974,0.0007646891],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003396296,"about_ca_system_score_gemma":0.0002989937,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002676315,"about_ca_topic_score_gemma":0.0002765724,"domain_scores_codex":[0.9997539,0.00006722176,0.00002174584,0.00003977329,0.00007334415,0.00004415845],"domain_scores_gemma":[0.9998928,0.00002520758,0.00003095001,0.0000149381,0.00001879936,0.00001721169],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003878376,0.0001758662,0.0004274999,0.0007614477,0.00003757866,0.000656878,0.00009706421,0.0004036274,0.9073416,0.003909822,0.001637682,0.08416304],"study_design_scores_gemma":[0.0004397604,0.002657816,0.002853791,0.0001828904,0.0001711041,0.005656438,0.00003645803,0.002024618,0.8448517,0.001521882,0.1395806,0.0000229215],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.5734581,0.3029127,0.08725783,0.002388213,0.002084553,0.0004441394,0.0006465144,0.001084769,0.02972307],"genre_scores_gemma":[0.8541867,0.09462459,0.0245139,0.0009051887,0.0005356817,0.0003798587,0.000890093,0.0001502479,0.0238137],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.001808776,"threshold_uncertainty_score":0.006050885,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1068494992367621,"score_gpt":0.390288394400051,"score_spread":0.2834388951632889,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}