{"id":"W1968791512","doi":"10.1038/nm.2871","title":"Bat3 promotes T cell responses and autoimmunity by repressing Tim-3–mediated cell death and exhaustion","year":2012,"lang":"en","type":"article","venue":"Nature Medicine","topic":"Galectins and Cancer Biology","field":"Immunology and Microbiology","cited_by":382,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; Ontario Institute for Cancer Research","funders":"National Institute of Neurological Disorders and Stroke; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"Biology; T cell; Population; Experimental autoimmune encephalomyelitis; Immunology; Cell biology; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000558342,0.0001758923,0.0002810983,0.00008706714,0.0002049337,0.000005400619,0.00007862713,0.0006677378,0.0002444864],"category_scores_gemma":[0.0002861448,0.0001240384,0.00001666626,0.0001000126,0.0003349267,0.00007110964,0.00006884769,0.0008763025,0.0000126333],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002235023,"about_ca_system_score_gemma":0.00002476764,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001318913,"about_ca_topic_score_gemma":0.000004618372,"domain_scores_codex":[0.9989244,0.0002717581,0.0001869575,0.0002452136,0.00003520022,0.000336407],"domain_scores_gemma":[0.9992755,0.0003150792,0.000113197,0.0001949494,0.00005108929,0.00005016797],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002141401,0.00007636721,0.03540565,0.00004667815,0.00002229288,0.000001621633,0.0006845961,1.484261e-8,0.9533292,0.00002883171,0.007604822,0.002585809],"study_design_scores_gemma":[0.004121404,0.001010768,0.3142478,0.0001486294,0.0001834579,0.0002830058,0.0005540911,0.000005338827,0.5038714,0.00008665917,0.1751291,0.0003583279],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8566911,0.1398621,0.00001958679,0.0006110504,0.0005847401,0.000149161,0.00001899694,0.00005626252,0.002007013],"genre_scores_gemma":[0.9947653,0.00110477,0.0000728474,0.0004766493,0.0001058613,0.000009008527,0.0001920677,0.00001325913,0.003260177],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4494578,"threshold_uncertainty_score":0.5150205,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009397397994680227,"score_gpt":0.2596589052184086,"score_spread":0.2502615072237284,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}