{"id":"W1968805055","doi":"10.1038/cgt.2008.96","title":"Retrovirally transduced murine T lymphocytes expressing FasL mediate effective killing of prostate cancer cells","year":2008,"lang":"en","type":"article","venue":"Cancer Gene Therapy","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ontario Institute for Cancer Research; University of Toronto","funders":"National Institutes of Health; Prostate Cancer Foundation","keywords":"LNCaP; Fas ligand; Cancer research; Cytotoxic T cell; Prostate cancer; Transduction (biophysics); Biology; Cancer cell; Apoptosis; Immunology; Cancer; In vitro; Programmed cell death","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003618308,0.0004610933,0.0004265434,0.0006053454,0.0002980749,0.0007977244,0.0003755209,0.000585143,0.002215231],"category_scores_gemma":[0.0002344314,0.0002681091,0.0004545382,0.0003246342,0.0003714246,0.0004008955,0.0003444822,0.001662645,0.000779293],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005686778,"about_ca_system_score_gemma":0.0005552473,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001446121,"about_ca_topic_score_gemma":0.001610072,"domain_scores_codex":[0.9995489,0.0000605138,0.0000285614,0.00006351094,0.0001282883,0.0001701748],"domain_scores_gemma":[0.9997744,0.0000775193,0.00003618208,0.00003643058,0.00002523537,0.00005013975],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001922811,0.0001543806,0.0001161964,0.00003531655,0.00001266647,0.00005906844,0.00007633454,0.000203244,0.9955001,0.0006269878,0.0001314526,0.002891959],"study_design_scores_gemma":[0.00004910407,0.0002817674,0.0004847782,0.000003983189,0.00001920527,0.0001474627,0.00002616996,0.0009920473,0.9960674,0.00005979684,0.001864613,0.000003601423],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9855058,0.002623721,0.005974659,0.000229081,0.0001137336,0.0001082454,0.0004904153,0.0003276393,0.004626674],"genre_scores_gemma":[0.9905248,0.0006769252,0.002116854,0.0000652331,0.00002379078,0.00004574244,0.0003459316,0.00004444135,0.006156334],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002215231,"threshold_uncertainty_score":0.007410705,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03039707577976087,"score_gpt":0.3157771978177423,"score_spread":0.2853801220379814,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}