{"id":"W1968847161","doi":"10.1074/jbc.m109.038612","title":"Redox Regulation of the Human Dual Specificity Phosphatase YVH1 through Disulfide Bond Formation","year":2009,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Windsor","funders":"","keywords":"Dual-specificity phosphatase; Phosphatase; Cysteine; Zinc finger; Chemistry; Oxidative stress; Zinc; Biochemistry; Redox; Oxidative phosphorylation; Thiol; Cell biology; Biophysics; Enzyme; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001686947,0.0002714694,0.0001241497,0.0001288858,0.0001298056,0.0002925475,0.000188214,0.0002267336,0.0003441659],"category_scores_gemma":[0.0001324641,0.0001059838,0.0001626331,0.00009459061,0.0002195905,0.0001969873,0.0002786097,0.000255596,0.0001157194],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003655262,"about_ca_system_score_gemma":0.0001536129,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004059521,"about_ca_topic_score_gemma":0.0004346255,"domain_scores_codex":[0.9998959,0.00001503347,0.000005381472,0.00004186104,0.00002489474,0.00001694665],"domain_scores_gemma":[0.9999473,0.000007771952,0.00001815033,0.000005207874,0.000010243,0.00001130282],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008477877,0.000008911585,0.0006245989,0.00002645471,0.000004795044,0.00003366524,0.0000177402,0.0001092583,0.9961708,0.0001695293,0.00004125476,0.002708246],"study_design_scores_gemma":[0.0000100225,0.00006972031,0.003753926,0.000001692107,0.000005828059,0.0001860629,0.00002307189,0.001742489,0.9923177,0.0001436366,0.001741572,0.000004207083],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99049,0.002929948,0.005469589,0.0001204844,0.00002144329,0.00001559159,0.0001548727,0.00007404332,0.0007240599],"genre_scores_gemma":[0.9958135,0.0008585242,0.002091528,0.00003256394,0.000006483556,0.000008384377,0.0001617804,0.00000781788,0.001019219],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004059521,"threshold_uncertainty_score":0.002652109,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02008109021719003,"score_gpt":0.2646472003577557,"score_spread":0.2445661101405657,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}