{"id":"W1968867081","doi":"10.1016/s0896-6273(01)00239-2","title":"Dominant-Negative c-Jun Promotes Neuronal Survival by Reducing BIM Expression and Inhibiting Mitochondrial Cytochrome c Release","year":2001,"lang":"en","type":"article","venue":"Neuron","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":563,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Neurological Institute and Hospital","funders":"","keywords":"Cytochrome c; Nerve growth factor; Apoptosis; Mitochondrion; Cell biology; Cytochrome; Biology; Molecular biology; Chemistry; Receptor; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007742665,0.0001756784,0.0001366861,0.00003599791,0.0001683429,0.00004087451,0.00007247621,0.0001324886,0.00001879964],"category_scores_gemma":[0.0001240549,0.0001587109,0.00005101677,0.00006717619,0.00005664084,0.00001103875,0.0001142464,0.0001169773,0.000002950427],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008121839,"about_ca_system_score_gemma":0.00002453093,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003404781,"about_ca_topic_score_gemma":0.000005713076,"domain_scores_codex":[0.9988191,0.0001013123,0.0001931214,0.0004895967,0.000158088,0.0002387505],"domain_scores_gemma":[0.9995509,0.00002709077,0.0001039934,0.0001781578,0.00004140938,0.0000984896],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001927707,0.00004464648,0.00006721857,0.00001230493,0.000004590437,0.00001146686,0.00003852662,0.00002800553,0.9952369,0.00002020479,0.0004534374,0.003889884],"study_design_scores_gemma":[0.001043799,0.0004444207,0.001276282,0.00004059034,0.00001331101,0.00005105796,0.00003441679,0.0004672432,0.9915938,0.0001055857,0.00472975,0.0001997137],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997474,0.0001777378,0.001294916,0.0001338638,0.0003205852,0.0002619175,0.00001222486,0.00001742749,0.0003074016],"genre_scores_gemma":[0.9977019,0.0002382558,0.0006655938,0.00006485506,0.0005202084,0.00001418915,0.00008558146,0.00003260563,0.0006768352],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004276313,"threshold_uncertainty_score":0.6472044,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008775789818156193,"score_gpt":0.2292041330722172,"score_spread":0.220428343254061,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}