{"id":"W1968872063","doi":"10.1006/viro.2000.0253","title":"The Effect of Mutant Peptide Cofactors on Adenovirus Protease Activity and Virus Infection","year":2000,"lang":"en","type":"article","venue":"Virology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Sherbrooke","funders":"Medical Research Council","keywords":"Peptide; Biology; Mutant; Protease; Biochemistry; Peptide sequence; In vitro; Cofactor; Cysteine; Enzyme; Virus; Molecular biology; Virology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00044849,0.0004748398,0.0004488533,0.0003069583,0.0003026925,0.0007153705,0.0006748832,0.0005521775,0.001732065],"category_scores_gemma":[0.001226487,0.0003097768,0.0002426045,0.000297468,0.0005816984,0.0005115533,0.0002508555,0.0007553991,0.0003328561],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006962506,"about_ca_system_score_gemma":0.0006085096,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003539077,"about_ca_topic_score_gemma":0.002039865,"domain_scores_codex":[0.9996353,0.00009504769,0.00005201771,0.00005843624,0.00006869704,0.00009039128],"domain_scores_gemma":[0.9987363,0.0006861307,0.000105811,0.0001539786,0.00008282057,0.0002348202],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002240166,0.0001322863,0.0003968411,0.00005312124,0.00001526493,0.0001277659,0.0000396088,0.0003009607,0.9944537,0.000681278,0.00005099387,0.00150786],"study_design_scores_gemma":[0.00003216604,0.0002534607,0.0006571595,0.000002932375,0.000006941345,0.0001765517,0.0000158868,0.0009669674,0.9973623,0.00006046377,0.000458245,0.000006909523],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971951,0.0009654997,0.0009811528,0.00004517726,0.00002958117,0.0000161628,0.0001898196,0.00004068989,0.0005368898],"genre_scores_gemma":[0.9974674,0.0002873447,0.001146406,0.00001435441,0.00001001111,0.000008823069,0.0003118883,0.00003165285,0.0007221698],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003539077,"threshold_uncertainty_score":0.007036984,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008003726199823683,"score_gpt":0.2777041235589989,"score_spread":0.2697003973591752,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}