{"id":"W1968889835","doi":"10.1016/j.trim.2009.04.001","title":"Anti-CD45RB monoclonal antibody induces immunologic toleration by suppressing dendritic cells","year":2009,"lang":"en","type":"article","venue":"Transplant Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"London Health Sciences Centre; Western University","funders":"London Health Sciences Centre","keywords":"Monoclonal antibody; Antigen; Cell sorting; T cell; Antibody; Immune tolerance; Dendritic cell; Immunology; Antigen presentation; Cell biology; Antigen-presenting cell; Transplantation; Biology; Immune system; Molecular biology; Chemistry; Flow cytometry; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002994518,0.0006128271,0.0005330004,0.0004863417,0.000268338,0.0004842304,0.0003500977,0.0004851019,0.001537075],"category_scores_gemma":[0.0002143994,0.0002672157,0.0004242289,0.0002164619,0.0002452736,0.0002691939,0.0002571579,0.00151686,0.0005380225],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002569983,"about_ca_system_score_gemma":0.0003307352,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000269342,"about_ca_topic_score_gemma":0.0005766318,"domain_scores_codex":[0.9995831,0.00007939345,0.00003177533,0.0000501576,0.00007008966,0.0001855648],"domain_scores_gemma":[0.9997409,0.00005914563,0.0000576053,0.00004968346,0.00001629015,0.00007638816],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008811692,0.0004370989,0.0003569451,0.00004350409,0.00001635226,0.0001077786,0.00001390578,0.0001407691,0.9936009,0.000281628,0.0001801285,0.003939769],"study_design_scores_gemma":[0.0003679522,0.002109324,0.005892137,0.00001170052,0.00007259574,0.0007212081,0.00003264703,0.00193901,0.9856512,0.0001978631,0.002995574,0.000008722816],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930831,0.001552225,0.002030096,0.000173868,0.0001393044,0.00004168635,0.0001234525,0.0002206956,0.002635503],"genre_scores_gemma":[0.9962847,0.0005479738,0.0007819782,0.0001128307,0.0000939489,0.00003885147,0.0001826982,0.0000404491,0.001916551],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001537075,"threshold_uncertainty_score":0.005142033,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01068838595098407,"score_gpt":0.2453772294608421,"score_spread":0.234688843509858,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}