{"id":"W1968889835","doi":"10.1016/j.trim.2009.04.001","title":"Anti-CD45RB monoclonal antibody induces immunologic toleration by suppressing dendritic cells","year":2009,"lang":"en","type":"article","venue":"Transplant Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"London Health Sciences Centre; Western University","funders":"London Health Sciences Centre","keywords":"Monoclonal antibody; Antigen; Cell sorting; T cell; Antibody; Immune tolerance; Dendritic cell; Immunology; Antigen presentation; Cell biology; Antigen-presenting cell; Transplantation; Biology; Immune system; Molecular biology; Chemistry; Flow cytometry; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0003427955,0.0006043161,0.0008724913,0.0003306868,0.0007128728,0.00008480592,0.0007562908,0.0009364106,0.001096627],"category_scores_gemma":[0.00002425027,0.00055758,0.0002571778,0.0002835828,0.0005665583,0.0004422618,0.0000368102,0.000992237,0.0007835211],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000697236,"about_ca_system_score_gemma":0.000120998,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009676059,"about_ca_topic_score_gemma":0.000002396276,"domain_scores_codex":[0.9964398,0.0007806269,0.0008507665,0.0006811128,0.00008783543,0.001159818],"domain_scores_gemma":[0.9986951,0.0003139657,0.0002483685,0.0006206617,0.00009279067,0.00002915697],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00125152,0.0005247235,0.0001989829,0.00001288732,0.0004362318,0.00004324645,0.0008827749,0.00001241071,0.9864905,0.0004060195,0.0008098618,0.008930863],"study_design_scores_gemma":[0.00301125,0.001102536,0.01854304,0.0001206674,0.0001082787,0.0008641015,0.0001946529,0.000008100003,0.9602319,0.0001575406,0.01499154,0.0006663928],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9419363,0.05321507,0.0009007294,0.0007780503,0.001680444,0.0004003841,0.0001732916,0.000343815,0.0005719233],"genre_scores_gemma":[0.99114,0.005557472,0.0001191879,0.000593674,0.00003640561,0.00002420529,0.0009454442,0.00004086261,0.001542768],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04920369,"threshold_uncertainty_score":0.9999945,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01068838595098407,"score_gpt":0.2453772294608421,"score_spread":0.234688843509858,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}