{"id":"W1968958817","doi":"10.1002/art.20253","title":"Efficacy and safety of leflunomide in the treatment of psoriatic arthritis and psoriasis: A multinational, double‐blind, randomized, placebo‐controlled clinical trial","year":2004,"lang":"en","type":"article","venue":"Arthritis & Rheumatism","topic":"Autoimmune and Inflammatory Disorders Research","field":"Medicine","cited_by":414,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Western Hospital; University of Toronto","funders":"","keywords":"Leflunomide; Medicine; Psoriatic arthritis; Psoriasis; Double blind; Placebo; Dermatology; Randomized controlled trial; Clinical trial; Arthritis; Placebo-controlled study; Internal medicine; Alternative medicine; Rheumatoid arthritis; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005795857,0.001430257,0.003414268,0.0004953572,0.0007557926,0.001071,0.0009607692,0.002676167,0.007465794],"category_scores_gemma":[0.004967244,0.0008022059,0.001783411,0.0005334652,0.001644704,0.001032026,0.0004735369,0.00203274,0.0009593049],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007309898,"about_ca_system_score_gemma":0.001515767,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007131739,"about_ca_topic_score_gemma":0.0011719,"domain_scores_codex":[0.9973915,0.001699118,0.0002063682,0.0003412132,0.0002019957,0.0001597931],"domain_scores_gemma":[0.9974693,0.0009202398,0.0007548355,0.0001936968,0.0001409205,0.0005210071],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9873685,0.003732814,0.0004478849,0.00039053,0.0004985613,0.00001443809,0.00002464215,0.00007331644,0.001055005,0.0000325184,0.0002347532,0.006127039],"study_design_scores_gemma":[0.9737409,0.02439672,0.0009858198,0.00002407545,0.0002758439,0.00001716856,0.000005466664,0.0001384821,0.0001739601,0.00003027364,0.0002054205,0.000005826686],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9744906,0.01033475,0.001203346,0.001275366,0.0007800233,0.008553089,0.001208375,0.0001182406,0.002036035],"genre_scores_gemma":[0.9775553,0.004045035,0.002450545,0.001608004,0.0008401442,0.01061357,0.0008496305,0.00002043846,0.002017344],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007465794,"threshold_uncertainty_score":0.03065175,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03674986616896051,"score_gpt":0.3457766156509602,"score_spread":0.3090267494819997,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}