{"id":"W1969017796","doi":"10.1038/jcbfm.2010.65","title":"<i>In vivo</i> and <i>in vitro</i> Validation of Reference Tissue Models for the mGluR <sub>5</sub> Ligand [ <sup>11</sup> C]ABP688","year":2010,"lang":"en","type":"article","venue":"Journal of Cerebral Blood Flow & Metabolism","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Douglas Mental Health University Institute; Montreal Neurological Institute and Hospital","funders":"","keywords":"Putamen; In vivo; Binding potential; Chemistry; Nuclear medicine; Cerebellum; Metabotropic glutamate receptor; Positron emission tomography; Metabotropic receptor; Glutamate receptor; Receptor; Internal medicine; Medicine; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001044297,0.0008362677,0.0003892022,0.0003338585,0.0002450891,0.0004953851,0.0005794501,0.0004889481,0.0008994152],"category_scores_gemma":[0.0009719405,0.0003631354,0.0002797225,0.0002114539,0.0004429817,0.0004200111,0.0002497161,0.0005599102,0.0006387097],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005235456,"about_ca_system_score_gemma":0.0003644313,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003629344,"about_ca_topic_score_gemma":0.004846283,"domain_scores_codex":[0.9992888,0.0002529904,0.00004271343,0.0001672294,0.0001740838,0.00007419683],"domain_scores_gemma":[0.9993524,0.0001359632,0.0001698382,0.0001234407,0.0001894985,0.00002878057],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001295745,0.00003017518,0.000349972,0.0000592485,0.00001198196,0.00002286252,0.00003296214,0.0003103648,0.9972938,0.0001075847,0.00004167993,0.001609731],"study_design_scores_gemma":[0.000008172045,0.0006183117,0.002312096,0.000008070832,0.00005605999,0.0001891862,0.00004477734,0.00195576,0.9935446,0.00003775437,0.001215552,0.000009824465],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8698334,0.003174052,0.1227732,0.0001450827,0.00007735808,0.0002281593,0.0007518133,0.0004056413,0.002611285],"genre_scores_gemma":[0.8900314,0.003380995,0.09912847,0.0001923735,0.0000367264,0.0005668619,0.002170394,0.0002417026,0.004251083],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003629344,"threshold_uncertainty_score":0.007216454,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02926889609807403,"score_gpt":0.2956614955885877,"score_spread":0.2663925994905136,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}