{"id":"W1969017796","doi":"10.1038/jcbfm.2010.65","title":"<i>In vivo</i> and <i>in vitro</i> Validation of Reference Tissue Models for the mGluR <sub>5</sub> Ligand [ <sup>11</sup> C]ABP688","year":2010,"lang":"en","type":"article","venue":"Journal of Cerebral Blood Flow & Metabolism","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Douglas Mental Health University Institute; Montreal Neurological Institute and Hospital","funders":"","keywords":"Putamen; In vivo; Binding potential; Chemistry; Nuclear medicine; Cerebellum; Metabotropic glutamate receptor; Positron emission tomography; Metabotropic receptor; Glutamate receptor; Receptor; Internal medicine; Medicine; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014687,0.0002659941,0.0006055695,0.0004425809,0.0001840399,0.0001115392,0.000863412,0.0001525642,0.00001691852],"category_scores_gemma":[0.0007776473,0.0001899868,0.0001360839,0.0007316712,0.0004172621,0.001280503,0.0001624118,0.001091931,0.000002923384],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008748952,"about_ca_system_score_gemma":0.0001991507,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001125991,"about_ca_topic_score_gemma":0.00001276668,"domain_scores_codex":[0.9969534,0.0003458385,0.0008753997,0.0004797503,0.000745956,0.0005996778],"domain_scores_gemma":[0.9977318,0.001083835,0.0004539136,0.0003236819,0.0002016838,0.0002050513],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003999342,0.0002597805,0.0001137455,0.00002860795,0.00000710591,0.0000620147,0.0002801994,0.001699505,0.9952008,0.0003537616,0.0002282038,0.001366313],"study_design_scores_gemma":[0.002823078,0.0001675815,0.0002214236,0.00001949319,0.00009448901,0.0003376315,0.00002735726,0.01030688,0.9824877,0.001574382,0.001776192,0.000163785],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966254,0.0002527461,0.0001207351,0.001581092,0.0007242201,0.0005639324,0.00006191403,0.000009049321,0.00006095024],"genre_scores_gemma":[0.9968939,0.001143271,0.0002990863,0.001179276,0.0003516658,0.00002727335,2.826391e-7,0.00003195048,0.00007332177],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01271312,"threshold_uncertainty_score":0.7747436,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02926889609807403,"score_gpt":0.2956614955885877,"score_spread":0.2663925994905136,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}