{"id":"W1969070909","doi":"10.1021/bi2016469","title":"Binding of Filamentous Actin to Anthrax Toxin Receptor 1 Decreases Its Association with Protective Antigen","year":2012,"lang":"en","type":"article","venue":"Biochemistry","topic":"Bacillus and Francisella bacterial research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Ectodomain; Cell biology; Actin remodeling; Actin-binding protein; Actin cytoskeleton; MDia1; Anthrax toxin; Biology; Cytoskeleton; Actin; Receptor; Biochemistry; Recombinant DNA; Cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009222489,0.0002622858,0.0001910072,0.00009474001,0.0001009934,0.0001587499,0.0001836712,0.0002044667,0.002032426],"category_scores_gemma":[0.0001476819,0.0001259024,0.0001088582,0.00005997497,0.0001419235,0.00008818907,0.0001428408,0.0003916544,0.0004704502],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002416981,"about_ca_system_score_gemma":0.0001211354,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006661275,"about_ca_topic_score_gemma":0.0008647945,"domain_scores_codex":[0.9998661,0.00003239227,0.000006398436,0.00001978575,0.0000327637,0.00004244136],"domain_scores_gemma":[0.9998937,0.00002726158,0.00002877631,0.00001068334,0.00001139167,0.0000282389],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005759564,0.0000197535,0.00006445296,0.00001049524,0.000001561386,0.00001042338,0.000003174619,0.00001406219,0.9995722,0.00001680424,0.00001895246,0.0002105233],"study_design_scores_gemma":[0.00001184276,0.0002037539,0.005563018,0.000003447923,0.000004938045,0.00009602572,0.00001495911,0.0006689652,0.992045,0.00001092505,0.001374821,0.000002212811],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977603,0.0004646179,0.0007723394,0.00007723464,0.00001319331,0.000009277375,0.0000814317,0.00003893719,0.0007826227],"genre_scores_gemma":[0.9945132,0.0003446541,0.001077704,0.00007116633,0.000008013262,0.00002451899,0.0004473599,0.00002914064,0.003484265],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002032426,"threshold_uncertainty_score":0.006799161,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01274612920530882,"score_gpt":0.2658625024748484,"score_spread":0.2531163732695396,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}