{"id":"W1969123018","doi":"10.1016/j.yrtph.2013.08.015","title":"Genotoxicity and subchronic oral toxicity of l-ornithine monohydrochloride","year":2013,"lang":"en","type":"article","venue":"Regulatory Toxicology and Pharmacology","topic":"Polyamine Metabolism and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"Intertek (Canada)","funders":"","keywords":"Genotoxicity; Ornithine; Chemistry; No-observed-adverse-effect level; Toxicity; Oral administration; Internal medicine; Endocrinology; Urea; Urine; Urea cycle; Excretion; Pharmacology; Biology; Biochemistry; Medicine; Arginine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003449681,0.0007889558,0.0003925495,0.0006726358,0.0003429152,0.0002236711,0.0003250411,0.0007122427,0.002245517],"category_scores_gemma":[0.0003186651,0.0003696789,0.0005714641,0.0005479228,0.0007255832,0.0002299445,0.0003112808,0.0009711852,0.0003473006],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004772411,"about_ca_system_score_gemma":0.0007554733,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005318036,"about_ca_topic_score_gemma":0.007371102,"domain_scores_codex":[0.9995791,0.0001314368,0.0000397173,0.00006504235,0.00007908964,0.000105551],"domain_scores_gemma":[0.9996985,0.00008333012,0.00005916614,0.00006351222,0.00003932979,0.00005620038],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001822038,0.0001908636,0.001072792,0.00006003424,0.00002945646,0.0002685516,0.00009118797,0.0002505378,0.9931287,0.00009808087,0.00006994852,0.00291777],"study_design_scores_gemma":[0.00005257034,0.003527047,0.006580756,0.00001332273,0.0000583244,0.0002122783,0.0001014039,0.0002647615,0.9885277,0.00004518356,0.0006071581,0.000009560285],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957345,0.001309006,0.0009164579,0.00006237628,0.00003076392,0.00003945214,0.0003317554,0.00003861943,0.001537016],"genre_scores_gemma":[0.9940776,0.001154499,0.0007167729,0.0000479846,0.00001083374,0.00005549467,0.0005081409,0.00001491293,0.003413877],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005318036,"threshold_uncertainty_score":0.01057416,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008615492709957569,"score_gpt":0.2613412477990213,"score_spread":0.2527257550890638,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}