{"id":"W1969124154","doi":"10.1038/msb.2011.68","title":"The MHC I immunopeptidome conveys to the cell surface an integrative view of cellular regulation","year":2011,"lang":"en","type":"article","venue":"Molecular Systems Biology","topic":"vaccines and immunoinformatics approaches","field":"Biochemistry, Genetics and Molecular Biology","cited_by":131,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Biology; Computational biology; Cell biology; Major histocompatibility complex; Immunology; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001587129,0.0002664766,0.0003111912,0.0001787215,0.0002097921,0.0009706185,0.0001919608,0.000363515,0.0007119247],"category_scores_gemma":[0.0001521141,0.0001573465,0.0001921249,0.0001397349,0.0005540227,0.0006099135,0.000231692,0.0006071988,0.0003194307],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003591661,"about_ca_system_score_gemma":0.0001542233,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001718061,"about_ca_topic_score_gemma":0.0001848699,"domain_scores_codex":[0.9998938,0.00001467581,0.000003877155,0.00004168101,0.00003257759,0.0000133643],"domain_scores_gemma":[0.9999236,0.00001790249,0.00002656716,0.00001094689,0.00001021461,0.00001077021],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004143746,0.0000046532,0.0002473739,0.00003502467,0.00000525675,0.00002759801,0.00001172741,0.0001843546,0.9952683,0.001132827,0.00005508881,0.002986455],"study_design_scores_gemma":[0.000005392887,0.0001005071,0.004831346,0.000007861517,0.00001710696,0.0002387524,0.00004397365,0.003756004,0.9834751,0.001381854,0.006130099,0.00001204309],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9289728,0.009256039,0.05317795,0.000979059,0.0001440697,0.000024238,0.0006079864,0.0003242526,0.006513552],"genre_scores_gemma":[0.9795294,0.002986903,0.01530089,0.0001778046,0.00003902843,0.00001958307,0.0002042967,0.00003115663,0.001710856],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009706185,"threshold_uncertainty_score":0.002605915,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01351410005063318,"score_gpt":0.222003433229303,"score_spread":0.2084893331786699,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}