{"id":"W1969124154","doi":"10.1038/msb.2011.68","title":"The MHC I immunopeptidome conveys to the cell surface an integrative view of cellular regulation","year":2011,"lang":"en","type":"article","venue":"Molecular Systems Biology","topic":"vaccines and immunoinformatics approaches","field":"Biochemistry, Genetics and Molecular Biology","cited_by":131,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Biology; Computational biology; Cell biology; Major histocompatibility complex; Immunology; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007655016,0.0002181887,0.0002565034,0.00002695872,0.0001656832,0.00003178145,0.0006349791,0.0001814188,0.000007696355],"category_scores_gemma":[0.00004288157,0.0001178363,0.0001158012,0.0001408495,0.00012121,0.000006768885,0.0001895189,0.0001070213,0.00002393966],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000124167,"about_ca_system_score_gemma":0.00005189479,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002648505,"about_ca_topic_score_gemma":0.00002527532,"domain_scores_codex":[0.9984715,0.00038474,0.0005073939,0.0002646556,0.00008967293,0.0002820633],"domain_scores_gemma":[0.9985068,0.0000197068,0.0002656814,0.0009581475,0.0001921801,0.00005741253],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006702028,0.00003735296,0.0001570442,0.00002679631,0.00008314995,4.954396e-7,0.0006615259,0.0001460429,0.9950148,0.002856458,0.000238649,0.0007106542],"study_design_scores_gemma":[0.000338274,0.001000889,0.0004305199,0.00002655187,0.00003119844,0.00001379187,0.001755832,0.000855114,0.9578676,0.00009760945,0.03734615,0.0002364167],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9354692,0.009799334,0.05022657,0.00009629272,0.0004708735,0.000905572,0.00002404745,0.0000124402,0.002995751],"genre_scores_gemma":[0.9985845,0.0001801096,0.0004034463,0.00009763393,0.00005077198,0.00005061071,0.0001285254,0.0000236098,0.0004807593],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06311541,"threshold_uncertainty_score":0.4805223,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01351410005063318,"score_gpt":0.222003433229303,"score_spread":0.2084893331786699,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}