{"id":"W1969167989","doi":"10.5339/qfarf.2012.aesnp9","title":"Efficient manufacturing of viral vectors for cancer therapies","year":2012,"lang":"en","type":"article","venue":"Qatar Foundation Annual Research Forum Volume 2012 Issue 1","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"","keywords":"HEK 293 cells; Oncolytic virus; Genetic enhancement; Viral vector; Transfection; Cell culture; Computational biology; Virus; Virology; Computer science; Medicine; Biology; Gene; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001504341,0.0006814704,0.0006974964,0.001150996,0.0004775167,0.001726966,0.0007120452,0.000925757,0.002373186],"category_scores_gemma":[0.0009855466,0.0005672022,0.0006140548,0.0008595735,0.0004548439,0.0008405597,0.0008583998,0.001757983,0.003536831],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008290219,"about_ca_system_score_gemma":0.0005766246,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003567044,"about_ca_topic_score_gemma":0.0006130884,"domain_scores_codex":[0.9983851,0.0003027065,0.0001700212,0.0001799604,0.0008523175,0.0001099658],"domain_scores_gemma":[0.9997179,0.00005826643,0.00006826903,0.00005329057,0.0000809133,0.00002127298],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008678185,0.0000783833,0.0002132763,0.0006618803,0.00003273931,0.0002465929,0.0001821691,0.001231307,0.8991749,0.01304946,0.00539554,0.079647],"study_design_scores_gemma":[0.00003613772,0.0003991596,0.0005571713,0.0001454978,0.00003979337,0.0009395597,0.00005596441,0.002705861,0.7643866,0.002974366,0.2277154,0.00004437264],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.06479724,0.04435462,0.8520938,0.001560818,0.00171425,0.002264068,0.003560429,0.002541034,0.02711369],"genre_scores_gemma":[0.2440356,0.05478008,0.6541732,0.000800673,0.0003209907,0.002001098,0.008012919,0.0007232606,0.03515231],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.002373186,"threshold_uncertainty_score":0.007955849,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0376630507953698,"score_gpt":0.3885552562156193,"score_spread":0.3508922054202495,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}