{"id":"W1969167989","doi":"10.5339/qfarf.2012.aesnp9","title":"Efficient manufacturing of viral vectors for cancer therapies","year":2012,"lang":"en","type":"article","venue":"Qatar Foundation Annual Research Forum Volume 2012 Issue 1","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"","keywords":"HEK 293 cells; Oncolytic virus; Genetic enhancement; Viral vector; Transfection; Cell culture; Computational biology; Virus; Virology; Computer science; Medicine; Biology; Gene; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001936848,0.0001805293,0.0001924946,0.0002248244,0.0003076118,0.00004540808,0.0004099279,0.0001535383,0.001181443],"category_scores_gemma":[0.0002112341,0.0001690217,0.0001236048,0.000157756,0.0003050333,0.00003206126,0.0002141209,0.0002080147,0.0001942867],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009854413,"about_ca_system_score_gemma":0.0001967057,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002401997,"about_ca_topic_score_gemma":0.0003201787,"domain_scores_codex":[0.99738,0.0002610919,0.0002840596,0.0003438147,0.0006891031,0.001041921],"domain_scores_gemma":[0.9985682,0.00006818914,0.00009062407,0.0004874188,0.0005620139,0.0002235177],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.006474531,0.000753723,0.00913184,0.0002467208,0.0004310896,6.995492e-7,0.002324956,0.001111794,0.7500023,0.0004184634,0.07304547,0.1560584],"study_design_scores_gemma":[0.0005597898,0.00143263,0.002037604,0.00001469123,0.000006851559,9.758929e-7,0.0008422488,0.0003268862,0.4342088,0.00005013572,0.5603437,0.0001756857],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927877,0.003490109,0.0008673607,0.001122407,0.0003521982,0.0008580972,0.000235628,0.00001692624,0.0002695306],"genre_scores_gemma":[0.9895436,0.0002622537,0.0003051499,0.00007817464,0.0007811895,0.0002600623,0.0002967917,0.00005595902,0.008416782],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4872983,"threshold_uncertainty_score":0.9997316,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0376630507953698,"score_gpt":0.3885552562156193,"score_spread":0.3508922054202495,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}