{"id":"W1969222256","doi":"10.1002/neu.10234","title":"Selective involvement of the PI3K/PKB/bad pathway in retinal cell death","year":2003,"lang":"en","type":"article","venue":"Journal of Neurobiology","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro; Canadian Institutes of Health Research; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Anisomycin; Biology; Protein kinase B; Cell biology; Programmed cell death; PI3K/AKT/mTOR pathway; Forskolin; LY294002; Phosphorylation; Signal transduction; Protein kinase A; Retina; Kinase; Apoptosis; Biochemistry; Neuroscience; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000129816,0.0003304572,0.0002077987,0.0002950854,0.0002172611,0.000293169,0.0001107007,0.0001960553,0.0007340889],"category_scores_gemma":[0.0001191693,0.0001600707,0.0001547734,0.0001204387,0.0002227084,0.0003111493,0.0002542245,0.00037761,0.0002252176],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002544073,"about_ca_system_score_gemma":0.0002338311,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001925738,"about_ca_topic_score_gemma":0.0003741024,"domain_scores_codex":[0.9998904,0.0000168231,0.000009865495,0.00002413088,0.00002424826,0.00003445206],"domain_scores_gemma":[0.9999253,0.000007729966,0.00001955568,0.00001013813,0.000008077166,0.00002917968],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001991911,0.00001208386,0.0005740885,0.00003796817,0.00000339315,0.0001262462,0.00001189158,0.00003482697,0.9973059,0.0001536478,0.00001277913,0.001528102],"study_design_scores_gemma":[0.00003904843,0.0003793222,0.0223728,0.00000677886,0.00002532274,0.001034924,0.00004194602,0.0004819137,0.9741236,0.0002682177,0.001220195,0.000005975737],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934907,0.003356777,0.001752064,0.00006273729,0.00001563593,0.00001312832,0.0001187272,0.00003344795,0.001156866],"genre_scores_gemma":[0.9966893,0.001322398,0.0007911277,0.00002276366,0.000005763584,0.0000147029,0.0001164863,0.000004667449,0.001032717],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007340889,"threshold_uncertainty_score":0.002455771,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009580625968837665,"score_gpt":0.216831039590934,"score_spread":0.2072504136220963,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}