{"id":"W1969222256","doi":"10.1002/neu.10234","title":"Selective involvement of the PI3K/PKB/bad pathway in retinal cell death","year":2003,"lang":"en","type":"article","venue":"Journal of Neurobiology","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro; Canadian Institutes of Health Research; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Anisomycin; Biology; Protein kinase B; Cell biology; Programmed cell death; PI3K/AKT/mTOR pathway; Forskolin; LY294002; Phosphorylation; Signal transduction; Protein kinase A; Retina; Kinase; Apoptosis; Biochemistry; Neuroscience; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003021233,0.00009019957,0.0001581546,0.0000530092,0.00002722471,0.000002971112,0.0001393809,0.0001160686,0.00001093906],"category_scores_gemma":[0.00006210605,0.00005862216,0.0001172311,0.00008777879,0.00004054593,0.000002374146,0.00003858171,0.0001522448,5.265442e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001615341,"about_ca_system_score_gemma":0.0001147189,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004072202,"about_ca_topic_score_gemma":0.00001550304,"domain_scores_codex":[0.9990786,0.0002483927,0.0003409564,0.0001243596,0.00006849969,0.0001391469],"domain_scores_gemma":[0.9993533,0.00001660105,0.0003446832,0.0001404923,0.00011557,0.00002927909],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006836931,0.00009649384,0.007171269,0.000007814544,0.00001169862,0.000003586105,0.00003737735,0.0002719301,0.9915619,0.0004734941,0.0001456489,0.0001504067],"study_design_scores_gemma":[0.0007363743,0.001100994,0.02423695,0.00001522039,0.000009948846,0.0001040401,0.00003953567,0.000009018974,0.9613457,0.0005524845,0.01177763,0.00007213608],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978698,0.0002970482,0.0002967386,0.00007476905,0.0003650906,0.0000971621,0.000002320169,7.260646e-7,0.0009962918],"genre_scores_gemma":[0.9990541,0.000159446,0.0003169076,0.0001564942,0.00006320271,0.000001342389,0.000002404425,0.000008081716,0.0002380723],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03021624,"threshold_uncertainty_score":0.2390542,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009580625968837665,"score_gpt":0.216831039590934,"score_spread":0.2072504136220963,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}