{"id":"W1969251489","doi":"10.1074/jbc.m708466200","title":"IQGAP1 Stimulates Proliferation and Enhances Tumorigenesis of Human Breast Epithelial Cells","year":2007,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":135,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"","keywords":"IQGAP1; Carcinogenesis; Biology; Scaffold protein; Neoplastic transformation; Cancer research; Cell growth; Cell biology; Signal transduction; Cancer; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009996854,0.0002426401,0.0001695725,0.000342651,0.0001102171,0.0001505169,0.00007518566,0.0001303115,0.002215581],"category_scores_gemma":[0.00009328914,0.00008590968,0.000168984,0.0001987208,0.0001072324,0.00007120915,0.0002378549,0.0003720309,0.0006020967],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002167965,"about_ca_system_score_gemma":0.0001192484,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006798442,"about_ca_topic_score_gemma":0.001029065,"domain_scores_codex":[0.9999052,0.00001751386,0.000004263859,0.00001294995,0.0000353972,0.00002463988],"domain_scores_gemma":[0.9999429,0.00001270477,0.000008231326,0.000009409636,0.000007144847,0.0000196089],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007632956,0.00005028786,0.0002031417,0.00002921621,0.000003187723,0.0000473715,0.00001628767,0.00004862664,0.9965008,0.00007009726,0.0001644949,0.002790044],"study_design_scores_gemma":[0.00002381569,0.000581915,0.01231379,0.000008767846,0.00001420415,0.0003665854,0.00004132632,0.0007714623,0.9764209,0.00008385129,0.009369466,0.000003784752],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9880911,0.00351345,0.001253412,0.0002920609,0.000044414,0.00002259062,0.000689336,0.0001670667,0.005926621],"genre_scores_gemma":[0.9918261,0.00195237,0.001223747,0.0001379632,0.00002425243,0.00002802797,0.001493065,0.00003023271,0.00328432],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002215581,"threshold_uncertainty_score":0.007411897,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008045930270295987,"score_gpt":0.2409501165994512,"score_spread":0.2329041863291552,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}