{"id":"W1969251489","doi":"10.1074/jbc.m708466200","title":"IQGAP1 Stimulates Proliferation and Enhances Tumorigenesis of Human Breast Epithelial Cells","year":2007,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":135,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"","keywords":"IQGAP1; Carcinogenesis; Biology; Scaffold protein; Neoplastic transformation; Cancer research; Cell growth; Cell biology; Signal transduction; Cancer; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003595365,0.0001100967,0.0001949058,0.00001490157,0.00004365429,0.00001159575,0.0001349331,0.0001734113,0.00002014477],"category_scores_gemma":[0.00003492126,0.00008034702,0.00008912398,0.00003313824,0.0001135233,0.000002846869,0.00005278866,0.00008676606,2.9725e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001006391,"about_ca_system_score_gemma":0.00002985906,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001642263,"about_ca_topic_score_gemma":0.000001153383,"domain_scores_codex":[0.9992068,0.00001474921,0.000421508,0.0001319279,0.0000881557,0.000136897],"domain_scores_gemma":[0.999313,0.00001783936,0.0003523608,0.0000928037,0.0001429513,0.00008106385],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001061195,0.00007403659,0.005488383,0.00003173299,0.00003080506,0.000004673997,0.00001389435,0.00002617456,0.9935409,0.000006125023,0.00001735462,0.0006597593],"study_design_scores_gemma":[0.0003124966,0.0003259582,0.01090149,0.00001321545,0.00001365041,0.0001399195,0.0000649648,0.00002145663,0.9878253,0.0001642798,0.0001215829,0.00009569581],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989427,0.00032402,0.0004548016,0.00002041509,0.00004730005,0.00003887639,0.00002235536,0.000002004831,0.0001474907],"genre_scores_gemma":[0.998633,0.0002241164,0.0007460811,0.00001940954,0.0003009948,4.829308e-7,0.00001812865,0.000006193106,0.00005165463],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005715648,"threshold_uncertainty_score":0.3276456,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008045930270295987,"score_gpt":0.2409501165994512,"score_spread":0.2329041863291552,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}