{"id":"W1969279377","doi":"10.1016/j.ygeno.2013.07.003","title":"Gene conversions are under purifying selection in the carcinoembryonic antigen immunoglobulin gene families of primates","year":2013,"lang":"en","type":"article","venue":"Genomics","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Gene; Negative selection; Genetics; Gene family; Gene conversion; Carcinoembryonic antigen; Primate; Antibody; Gene expression; Genome","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002061269,0.0001219669,0.0002429307,0.000126355,0.0001182268,0.00002085102,0.0001730439,0.00007921671,0.0001536267],"category_scores_gemma":[0.00002246526,0.00008437323,0.00008956751,0.000235956,0.0001122658,0.00005547148,0.00008021905,0.0002365803,0.0001059767],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001006887,"about_ca_system_score_gemma":0.0001483037,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001981679,"about_ca_topic_score_gemma":0.00006270153,"domain_scores_codex":[0.9989712,0.00006342151,0.0002670876,0.000173068,0.0002266109,0.0002986322],"domain_scores_gemma":[0.9994709,0.00009438354,0.00008203298,0.0001732337,0.0001242024,0.00005519542],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001317554,0.0001423241,0.3293385,0.0001581744,0.0001027476,0.00001297712,0.001293049,0.0002448995,0.6661897,0.000178769,0.0009887225,0.001218465],"study_design_scores_gemma":[0.0005134281,0.0001096737,0.9194254,0.00002884357,0.00002484057,0.00007998816,0.002245316,0.0008283578,0.07493684,0.0002009654,0.00150495,0.0001014449],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948732,0.002228377,0.00004421395,0.001604524,0.00005415298,0.0004770802,0.00001781311,0.00001293368,0.0006877295],"genre_scores_gemma":[0.9947532,0.003096198,0.001083561,0.00041679,0.00009570057,0.00002084159,0.00003927092,0.00001434338,0.0004800836],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5912528,"threshold_uncertainty_score":0.3440641,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02752397901787065,"score_gpt":0.2756415369405458,"score_spread":0.2481175579226752,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}