{"id":"W1969296875","doi":"10.1016/j.molcel.2007.04.016","title":"RNA Helicase A Interacts with RISC in Human Cells and Functions in RISC Loading","year":2007,"lang":"en","type":"article","venue":"Molecular Cell","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":220,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institutes of Health; National Institute of Allergy and Infectious Diseases; Ontario HIV Treatment Network","keywords":"RNA-induced silencing complex; Biology; Dicer; Argonaute; RNA interference; RNA silencing; RNA; RNA Helicase A; Trans-acting siRNA; Gene silencing; Small interfering RNA; Cell biology; Molecular biology; Helicase; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002624009,0.0001966811,0.000294821,0.0005098053,0.000399005,0.0008058567,0.0002054337,0.0003998732,0.001885291],"category_scores_gemma":[0.0003792842,0.0002863961,0.0003140964,0.0004047104,0.000246864,0.0002256613,0.0001787257,0.0003175763,0.001005978],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005659485,"about_ca_system_score_gemma":0.0003831603,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001797008,"about_ca_topic_score_gemma":0.00123772,"domain_scores_codex":[0.9997388,0.00007461713,0.00001861657,0.00006297309,0.00005620039,0.00004875795],"domain_scores_gemma":[0.9997857,0.00007576704,0.00003070455,0.00004543827,0.0000299825,0.00003235444],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007093052,0.00005719156,0.002605171,0.00006371588,0.00004064228,0.0005520306,0.00007834736,0.0002229209,0.9875026,0.000725074,0.0006255783,0.006817497],"study_design_scores_gemma":[0.00005137036,0.0002440134,0.02132273,0.00001473545,0.00006060989,0.00330231,0.0001009595,0.002299053,0.9591494,0.0006029986,0.01283637,0.00001557906],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9768841,0.01273084,0.005082503,0.0003141425,0.00006717207,0.0000309254,0.0007137659,0.000214923,0.003961675],"genre_scores_gemma":[0.9921412,0.001421676,0.001995496,0.00009757408,0.00003353476,0.00001759026,0.001075591,0.00003205792,0.003185228],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001885291,"threshold_uncertainty_score":0.006306946,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005961392000084135,"score_gpt":0.2317747813076968,"score_spread":0.2258133893076127,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}