{"id":"W1969302053","doi":"10.1542/peds.2006-2783","title":"A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Metabolic and Respiratory Effects of Growth Hormone in Children With Cystic Fibrosis","year":2007,"lang":"en","type":"article","venue":"PEDIATRICS","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"Pfizer","keywords":"Medicine; Growth hormone treatment; Placebo; Cystic fibrosis; Internal medicine; Adverse effect; Dose; Vital capacity; Hormone; Gastroenterology; Endocrinology; Growth hormone; Lung; Lung function; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002316929,0.0016402,0.003792466,0.0005684987,0.000818555,0.0007886528,0.0009337704,0.002549407,0.006534843],"category_scores_gemma":[0.003402947,0.0007554542,0.001345629,0.0004775069,0.001720348,0.0009538161,0.0004738776,0.002252788,0.0008248012],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000522009,"about_ca_system_score_gemma":0.001918077,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005677373,"about_ca_topic_score_gemma":0.001028645,"domain_scores_codex":[0.9987867,0.0007274338,0.00009152995,0.0001853567,0.00009976927,0.0001090916],"domain_scores_gemma":[0.9981236,0.0005733887,0.0004892284,0.0001392715,0.0001358197,0.0005387263],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9826958,0.005721069,0.0004501913,0.0005691362,0.0003101636,0.00004196623,0.00003662898,0.0001473006,0.002710401,0.00006762346,0.0003862493,0.006863309],"study_design_scores_gemma":[0.9747901,0.02435416,0.0004347017,0.00001351725,0.00005976425,0.00001157328,0.000005155743,0.00008069271,0.0001305145,0.00001721442,0.00009924284,0.000003439526],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9829118,0.004324356,0.0008917704,0.0009769251,0.0008921731,0.007961581,0.0007779866,0.0001690101,0.001094342],"genre_scores_gemma":[0.967453,0.002773481,0.004327056,0.001549358,0.0009297796,0.02024265,0.001037185,0.00003086485,0.001656637],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006534843,"threshold_uncertainty_score":0.02186126,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01317327740099427,"score_gpt":0.3061393066011228,"score_spread":0.2929660292001285,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}