{"id":"W1969330771","doi":"10.1038/onc.2008.376","title":"Akt phosphorylation of La regulates specific mRNA translation in glial progenitors","year":2008,"lang":"en","type":"article","venue":"Oncogene","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; William Osler Health System","funders":"National Cancer Institute; National Institutes of Health; Memorial Sloan-Kettering Cancer Center","keywords":"Biology; Polysome; Protein kinase B; Translation (biology); Phosphorylation; Messenger RNA; Cell biology; Protein biosynthesis; RNA-binding protein; Molecular biology; AKT3; Signal transduction; RNA; Gene; AKT1; Biochemistry; Ribosome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001406441,0.00006675179,0.00008730365,0.00004749703,0.00003167939,0.000003993602,0.00006990134,0.00009311928,0.00001481565],"category_scores_gemma":[0.00001958521,0.00006571584,0.00004924024,0.0001089624,0.00005869165,0.000003630302,0.00001038022,0.00004678877,0.000003535273],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000117128,"about_ca_system_score_gemma":0.0000570958,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003623775,"about_ca_topic_score_gemma":0.0000302046,"domain_scores_codex":[0.9993811,0.00004633544,0.0001606172,0.000152993,0.0001266018,0.0001323989],"domain_scores_gemma":[0.9997401,0.00001140169,0.00003987283,0.0001304199,0.00003995748,0.00003828512],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001489492,0.00004435724,0.007634105,0.000006423254,0.000008682842,0.000006693835,0.00007979258,0.0000964621,0.978775,0.0000113527,0.000143907,0.0130443],"study_design_scores_gemma":[0.0005503726,0.0001241446,0.005829769,0.000008505057,0.000001809273,0.00001360956,0.00002517947,0.000114296,0.9872794,0.00001765878,0.00596443,0.00007079091],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996919,0.001379747,0.0001745174,0.00002985111,0.00003636674,0.0001277581,0.000004673947,0.000004169447,0.00132396],"genre_scores_gemma":[0.9981561,0.0003501693,0.000880365,0.000004781913,0.0001193255,0.000007547443,0.00005386536,0.00001053098,0.000417362],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01297351,"threshold_uncertainty_score":0.2679814,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02106228773805345,"score_gpt":0.2650687802745806,"score_spread":0.2440064925365271,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}