{"id":"W1969365651","doi":"10.1006/bbrc.2000.3475","title":"Hypoxia Induces the Expression of a 43-kDa Protein (PROXY-1) in Normal and Malignant Cells","year":2000,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":85,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"","keywords":"Downregulation and upregulation; Hypoxia (environmental); Messenger RNA; Biology; Molecular biology; Gene expression; Oxygen; Gene; Cell culture; Chemistry; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003892617,0.0001067586,0.0001454468,0.00004109965,0.0001646133,0.00002849817,0.0005203258,0.0001253399,0.00001645973],"category_scores_gemma":[0.00009048513,0.00007205963,0.00004632055,0.0002311797,0.0009565842,0.000007631534,0.0004728069,0.000308896,0.000003708408],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006690091,"about_ca_system_score_gemma":0.00007327094,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001721831,"about_ca_topic_score_gemma":0.0000170341,"domain_scores_codex":[0.9988148,0.0002333349,0.0002034611,0.0002621026,0.0002219582,0.0002643143],"domain_scores_gemma":[0.9989305,0.00008387103,0.0000340147,0.000747346,0.00009342063,0.0001109145],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000974644,0.0002050814,0.00002158291,0.00002335173,0.000006173767,1.269615e-7,0.00008491552,1.761771e-7,0.9901041,0.0002639737,0.0005503082,0.008642728],"study_design_scores_gemma":[0.0003233335,0.0001170041,0.001151902,0.00006027982,0.000004980117,0.00000193637,0.0001080029,0.00003622788,0.9649679,0.0003362289,0.03279425,0.00009795142],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930818,0.004863315,0.000002605324,0.00103456,0.00001303072,0.0003539925,0.00002912198,0.000004092277,0.0006174461],"genre_scores_gemma":[0.9923599,0.006434168,0.0004433485,0.00003689513,0.0001668624,0.0001257416,0.00002919764,0.000008870224,0.0003950515],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03224394,"threshold_uncertainty_score":0.3524574,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03317104903563687,"score_gpt":0.3186480220359382,"score_spread":0.2854769730003013,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}