{"id":"W1969378040","doi":"10.1021/op900142j","title":"The Solubility of Beclomethasone-17,21-dipropionate in Selected Organic Solvents: Experimental Measurement and Thermodynamic Modeling","year":2009,"lang":"en","type":"article","venue":"Organic Process Research & Development","topic":"Phase Equilibria and Thermodynamics","field":"Engineering","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"UNIQUAC; Solubility; Chemistry; Micronization; Supercritical fluid; Acetone; Gravimetric analysis; Methanol; Thermodynamics; Chromatography; Organic chemistry; Activity coefficient; Physical chemistry; Aqueous solution; Particle size; Non-random two-liquid model","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000365261,0.0003132943,0.0003181427,0.0002364828,0.0002303395,0.0002046801,0.0002409184,0.0002238801,0.0003923487],"category_scores_gemma":[0.0005173558,0.0001267667,0.0002298565,0.000412591,0.0002373561,0.0003733889,0.0001500025,0.0002031049,0.0001747733],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003303832,"about_ca_system_score_gemma":0.0003521368,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001752796,"about_ca_topic_score_gemma":0.001863399,"domain_scores_codex":[0.9997349,0.00003604266,0.00001932217,0.00004244422,0.0001467581,0.000020505],"domain_scores_gemma":[0.9998525,0.00005863955,0.00002769653,0.00001258221,0.00004453623,0.000004008994],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0001017366,0.00002565079,0.001585294,0.0001962866,0.00001364904,0.00008803153,0.00005401961,0.004694371,0.9876429,0.0002794415,0.00004241443,0.005276181],"study_design_scores_gemma":[0.000003181078,0.0001301891,0.002002015,0.000006669501,0.00001153951,0.00008626495,0.00003380118,0.01150478,0.9853958,0.00007283522,0.0007463713,0.000006453166],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.978485,0.003333259,0.01571183,0.00007674695,0.00001362126,0.00003715103,0.0004692904,0.00007230503,0.001800655],"genre_scores_gemma":[0.9902773,0.002130816,0.006670628,0.00001564922,0.000006950682,0.00004468708,0.0003841974,0.00001317804,0.0004566311],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001752796,"threshold_uncertainty_score":0.003485203,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03448436526281984,"score_gpt":0.2998856509263754,"score_spread":0.2654012856635555,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}