{"id":"W1969382620","doi":"10.1038/icb.2008.71","title":"Getting a <i>GRASP</i> on CASP: properties and role of the cytohesin‐associated scaffolding protein in immunity","year":2008,"lang":"en","type":"review","venue":"Immunology and Cell Biology","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"CASP; Sorting nexin; Scaffold protein; Biology; PDZ domain; Immune system; Signal transducing adaptor protein; Context (archaeology); Endocytic cycle; Cell biology; Computational biology; Signal transduction; Immunology; Protein structure; Genetics; Protein structure prediction; Intracellular; Endocytosis; Cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002057913,0.0003053944,0.0007373791,0.0000901176,0.0001552706,0.00000515592,0.0002223077,0.0009489862,0.00000279659],"category_scores_gemma":[0.00005145269,0.0002083339,0.0001706686,0.0001146835,0.0005215865,0.000002578284,0.0001547961,0.0003439467,0.000001061116],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001884511,"about_ca_system_score_gemma":0.0001158959,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001179739,"about_ca_topic_score_gemma":0.00009509593,"domain_scores_codex":[0.9983373,0.0005190817,0.0004383975,0.0003836202,0.00003856419,0.0002830783],"domain_scores_gemma":[0.9992936,0.00002945414,0.0003127737,0.0003107378,0.00003203707,0.00002142889],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008332387,0.0001063939,0.0007794479,0.0006141062,0.0001447294,0.000003779043,0.0001391228,3.562559e-7,0.9126053,0.00005223837,0.000001301642,0.08546986],"study_design_scores_gemma":[0.001630389,0.001403654,0.001545878,0.004619324,0.0002887693,0.0001970887,0.0003208662,0.000006658944,0.194191,0.00018422,0.7945537,0.001058414],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.4046362,0.5947769,0.000001339526,0.000006905302,0.0000423337,0.0003467579,0.00001314516,0.000004412681,0.0001720891],"genre_scores_gemma":[0.2838123,0.7156494,0.000006619192,0.00001588129,0.0000197023,0.00004693372,0.0003544583,0.00001768756,0.00007699207],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7945524,"threshold_uncertainty_score":0.8495608,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01676000825799744,"score_gpt":0.2182040341176922,"score_spread":0.2014440258596947,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}