{"id":"W1969421326","doi":"10.1167/iovs.07-1546","title":"Divergent Phenotypes of Vision and Accessory Visual Function in Mice with Visual Cycle Dysfunction (<i>Rpe65<sup><i>rd12</i></sup></i>) or Retinal Degeneration (<i>rd/rd</i>)","year":2008,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Howard Hughes Medical Institute","keywords":"Retinal degeneration; RPE65; Retinal; Visual phototransduction; Retina; Neuroscience; Macular degeneration; Cis-trans-Isomerases; Biology; Ophthalmology; Retinal pigment epithelium; Medicine; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003420452,0.001045556,0.0003099893,0.001081984,0.0002357066,0.0005736065,0.0004416502,0.000566168,0.001803592],"category_scores_gemma":[0.0002748498,0.0003997144,0.0004732803,0.0002130262,0.0007634462,0.0003988707,0.0006045164,0.001385923,0.0004584551],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004707331,"about_ca_system_score_gemma":0.0003203358,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007535858,"about_ca_topic_score_gemma":0.001337241,"domain_scores_codex":[0.9995248,0.00003865978,0.00008523564,0.0001540837,0.000131042,0.00006617463],"domain_scores_gemma":[0.9990415,0.00008748281,0.0004826717,0.00007878355,0.00006470257,0.0002448486],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001438427,0.00002639875,0.0004429164,0.00003020864,0.000008337115,0.00009923535,0.00002995829,0.00003191368,0.9980683,0.0001574128,0.00002582825,0.000935596],"study_design_scores_gemma":[0.0000735145,0.0009543544,0.03347265,0.00005068354,0.00007537133,0.003165458,0.000116405,0.0006921599,0.9591887,0.0002865067,0.001895418,0.00002877206],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9899559,0.001458011,0.004584228,0.0001035397,0.00002215248,0.00004430139,0.001061339,0.0002459796,0.00252454],"genre_scores_gemma":[0.9843493,0.0009852259,0.006705007,0.0001618546,0.0000108261,0.0001078727,0.001289716,0.0002379202,0.006152367],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001803592,"threshold_uncertainty_score":0.006033659,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01858037138498145,"score_gpt":0.2862426004216356,"score_spread":0.2676622290366542,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}