{"id":"W1969421326","doi":"10.1167/iovs.07-1546","title":"Divergent Phenotypes of Vision and Accessory Visual Function in Mice with Visual Cycle Dysfunction (<i>Rpe65<sup><i>rd12</i></sup></i>) or Retinal Degeneration (<i>rd/rd</i>)","year":2008,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Howard Hughes Medical Institute","keywords":"Retinal degeneration; RPE65; Retinal; Visual phototransduction; Retina; Neuroscience; Macular degeneration; Cis-trans-Isomerases; Biology; Ophthalmology; Retinal pigment epithelium; Medicine; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.0006118319,0.0003405155,0.0003175613,0.0002508402,0.0004654196,0.00003938931,0.0002537523,0.0002041147,0.00005094432],"category_scores_gemma":[0.0003026143,0.0002707055,0.00004708494,0.0008793414,0.002733303,0.0001245445,0.0002663492,0.0001919247,0.000008935342],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006025428,"about_ca_system_score_gemma":0.0005581637,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001594461,"about_ca_topic_score_gemma":0.00005040205,"domain_scores_codex":[0.9973853,0.0002343534,0.0004601075,0.0009244349,0.0005092352,0.0004865589],"domain_scores_gemma":[0.9989828,0.00005679028,0.000273028,0.0001546373,0.0003159238,0.0002167742],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001519991,0.0002398788,0.1865157,0.00002741754,0.00002293456,0.00003461872,0.0005133876,0.000978119,0.8096147,0.00002038765,0.00007719997,0.0004357321],"study_design_scores_gemma":[0.001411246,0.005373278,0.4022419,0.00006973653,0.00003012924,0.000281452,0.0005298621,0.003072673,0.5861806,0.0002638052,0.00008650241,0.0004587698],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984555,0.0002349525,0.0001974262,0.0001266186,0.0001387927,0.0003595908,0.000004737793,0.00001757493,0.0004648662],"genre_scores_gemma":[0.9982472,0.00009961665,0.00103106,0.0001982763,0.00008731459,0.00004354512,0.00006823445,0.00002259166,0.0002021613],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.223434,"threshold_uncertainty_score":0.9999807,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01858037138498145,"score_gpt":0.2862426004216356,"score_spread":0.2676622290366542,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}