{"id":"W1969438694","doi":"10.1016/j.jsbmb.2014.06.001","title":"All sex steroids are made intracellularly in peripheral tissues by the mechanisms of intracrinology after menopause","year":2014,"lang":"en","type":"review","venue":"The Journal of Steroid Biochemistry and Molecular Biology","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":218,"is_retracted":false,"has_abstract":false,"ca_institutions":"Theratechnologies (Canada)","funders":"","keywords":"Menopause; Estrogen; Endocrinology; Internal medicine; Steroid; Hormone; Sex steroid; Secretion; Biology; Dehydroepiandrosterone; Enzyme; Endometrium; Endometrial cancer; Testosterone (patch); Estrone; Androgen; Medicine; Cancer; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008479725,0.0005341301,0.001265309,0.00007535004,0.00005448879,0.00002390813,0.0007998891,0.001069466,0.000007548608],"category_scores_gemma":[0.00006559453,0.0002973004,0.0003037555,0.000102282,0.0005756512,0.000004998459,0.0003339923,0.0009004105,0.000001384788],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003107152,"about_ca_system_score_gemma":0.00009969949,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008661113,"about_ca_topic_score_gemma":0.000001726626,"domain_scores_codex":[0.9971403,0.0009321725,0.0009832797,0.0003709773,0.0001457509,0.0004274991],"domain_scores_gemma":[0.9980306,0.0000813371,0.001116271,0.0005698734,0.000087829,0.000114092],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003029903,0.0001075011,0.00001797862,0.001423765,0.0008960548,0.00007267747,0.00008714197,0.000001509004,0.9519652,0.00002310183,0.0004229578,0.04467916],"study_design_scores_gemma":[0.001227059,0.00216173,0.000003835562,0.001707812,0.00138387,0.003527393,0.0002161581,0.000003231994,0.7662554,0.0002806802,0.2225635,0.0006693606],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1342868,0.8639676,0.00110941,0.0001521414,0.0001326438,0.0002848682,0.00004087915,0.000003118347,0.0000225736],"genre_scores_gemma":[0.125902,0.8732822,0.0001164001,0.0002464611,0.0001579446,0.00002243414,0.00008813105,0.00004970605,0.0001347335],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.2221406,"threshold_uncertainty_score":0.9999479,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006773720425405593,"score_gpt":0.2667747329393448,"score_spread":0.2600010125139392,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}