{"id":"W1969528252","doi":"10.1002/dvg.20746","title":"A tryptophan hydroxlyase 1 reporter that directs Cre recombinase extinguishable placental alkaline phosphatase expression in serotonergic (5‐HT) neurons and peripheral tissues","year":2011,"lang":"en","type":"article","venue":"genesis","topic":"Polyamine Metabolism and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Research Chairs; Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"Canadian Institutes of Health Research","keywords":"TPH2; Serotonergic; Placental alkaline phosphatase; Tryptophan hydroxylase; Biology; Serotonin; Molecular biology; Cre recombinase; Serotonin Plasma Membrane Transport Proteins; Endocrinology; Internal medicine; Alkaline phosphatase; Genetically modified mouse; Transgene; Biochemistry; Gene; Receptor; Enzyme; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001127121,0.0001933435,0.0001840781,0.00004439354,0.00009687022,0.00002154015,0.0001350153,0.0001065552,0.0001738166],"category_scores_gemma":[0.00003950632,0.0001837538,0.00005339874,0.00008571323,0.00005779562,0.00001144379,0.0001506613,0.00005430026,0.000005859262],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007628682,"about_ca_system_score_gemma":0.00002732215,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002740902,"about_ca_topic_score_gemma":0.00007230375,"domain_scores_codex":[0.9988742,0.00006099598,0.0002218626,0.0004780427,0.00008830745,0.000276605],"domain_scores_gemma":[0.9992988,0.000006560285,0.0001015463,0.0004267691,0.00002186727,0.0001444183],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000201371,0.0004279709,0.02229503,0.00003526737,0.0000197654,0.0001115753,0.000457549,0.00001013119,0.9678114,0.00002260774,0.003405848,0.005201467],"study_design_scores_gemma":[0.0009181323,0.00009595009,0.02378216,0.00002053382,0.00002245982,0.00006152475,0.0001778554,0.00008419776,0.945039,0.000048821,0.02948445,0.0002648886],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994471,0.004176408,0.0000693578,0.00003450736,0.0001101776,0.0002979782,0.00006667576,0.00002403956,0.0007498165],"genre_scores_gemma":[0.9954011,0.000682659,0.001706029,0.0001764879,0.0001147125,0.0001781318,0.0002681796,0.00003162281,0.001441066],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0260786,"threshold_uncertainty_score":0.7493261,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02020607618436809,"score_gpt":0.2454847296312999,"score_spread":0.2252786534469318,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}