{"id":"W1969528252","doi":"10.1002/dvg.20746","title":"A tryptophan hydroxlyase 1 reporter that directs Cre recombinase extinguishable placental alkaline phosphatase expression in serotonergic (5‐HT) neurons and peripheral tissues","year":2011,"lang":"en","type":"article","venue":"genesis","topic":"Polyamine Metabolism and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Research Chairs; Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"Canadian Institutes of Health Research","keywords":"TPH2; Serotonergic; Placental alkaline phosphatase; Tryptophan hydroxylase; Biology; Serotonin; Molecular biology; Cre recombinase; Serotonin Plasma Membrane Transport Proteins; Endocrinology; Internal medicine; Alkaline phosphatase; Genetically modified mouse; Transgene; Biochemistry; Gene; Receptor; Enzyme; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003072013,0.0006033013,0.0003395537,0.0005900096,0.0002989122,0.0004182541,0.0007935427,0.0007911127,0.002960007],"category_scores_gemma":[0.0001914153,0.0004562543,0.0004727156,0.0002784586,0.0005862847,0.000321371,0.0003660549,0.00129025,0.001006612],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004623428,"about_ca_system_score_gemma":0.0003731565,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001093961,"about_ca_topic_score_gemma":0.001709483,"domain_scores_codex":[0.9997042,0.00003079004,0.00002544257,0.0001089671,0.00007743132,0.00005321295],"domain_scores_gemma":[0.9997494,0.00003792927,0.0001038922,0.00002936119,0.00002253316,0.00005693982],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004029443,0.0000216948,0.00006117488,0.00002527942,0.000002915458,0.00005415108,0.00001771774,0.00003678737,0.9985532,0.0001942768,0.00005453277,0.0009378918],"study_design_scores_gemma":[0.00005760017,0.0002125956,0.001524877,0.00001461322,0.00002469799,0.0004960974,0.00002716007,0.001291224,0.9892519,0.00007843318,0.007013514,0.000007366622],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8819066,0.001194167,0.1045215,0.0004264468,0.0002277274,0.0004670141,0.003142635,0.001390974,0.006723003],"genre_scores_gemma":[0.8991491,0.001610701,0.06227664,0.0001983204,0.00003941397,0.0006393186,0.004035353,0.0003528424,0.03169826],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002960007,"threshold_uncertainty_score":0.009902179,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02020607618436809,"score_gpt":0.2454847296312999,"score_spread":0.2252786534469318,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}