{"id":"W1969579534","doi":"10.1161/atvbaha.115.305534","title":"Myocardial Infarction–Associated SNP at 6p24 Interferes With MEF2 Binding and Associates With <i>PHACTR1</i> Expression Levels in Human Coronary Arteries","year":2015,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":89,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of General Medical Sciences; National Human Genome Research Institute; Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research","keywords":"Biology; Genome-wide association study; Locus (genetics); Genetics; Single-nucleotide polymorphism; Expression quantitative trait loci; SNP; Gene; Genotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002822275,0.0005315958,0.0002864004,0.0004046508,0.0002266322,0.0002670995,0.0002837832,0.0004625996,0.003717577],"category_scores_gemma":[0.0004535844,0.0001431598,0.0005078156,0.0003507108,0.000213723,0.00006126666,0.0001947643,0.0004418784,0.0005469853],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001154395,"about_ca_system_score_gemma":0.000068965,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003868,"about_ca_topic_score_gemma":0.0004971831,"domain_scores_codex":[0.9997095,0.00006589476,0.00003073522,0.000108922,0.00005220983,0.00003272107],"domain_scores_gemma":[0.9997378,0.00007128549,0.0001153543,0.00002633318,0.00001129946,0.00003785381],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00161729,0.0002158148,0.03999005,0.0001041338,0.0003194805,0.001441903,0.00005635479,0.0004058692,0.9479995,0.0001960537,0.0004478344,0.00720576],"study_design_scores_gemma":[0.0003467436,0.00151131,0.6726717,0.00007750277,0.0007629404,0.009014979,0.00007394788,0.004601782,0.3052064,0.0006841876,0.004999739,0.00004874116],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950805,0.0005969377,0.00250891,0.0001475987,0.00003646987,0.00002821712,0.0007333169,0.00006190614,0.0008063187],"genre_scores_gemma":[0.99698,0.0001788415,0.001525043,0.0001147011,0.00002751638,0.00003185087,0.000638505,0.00002545526,0.0004780527],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003717577,"threshold_uncertainty_score":0.01243651,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0498799723424642,"score_gpt":0.2863490665363343,"score_spread":0.2364690941938701,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}