{"id":"W1969606058","doi":"10.1038/mi.2012.12","title":"Neisseria gonorrhoeae selectively suppresses the development of Th1 and Th2 cells, and enhances Th17 cell responses, through TGF-β-dependent mechanisms","year":2012,"lang":"en","type":"article","venue":"Mucosal Immunology","topic":"Bacterial Infections and Vaccines","field":"Immunology and Microbiology","cited_by":100,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; University at Buffalo; National Institutes of Health; John R. Oishei Foundation; Canadian Institutes of Health Research; U.S. Department of Veterans Affairs","keywords":"Neisseria gonorrhoeae; Immune system; Immunity; Acquired immune system; Immunology; Biology; Innate immune system; Microbiology; Pathogen; Transforming growth factor; Blockade; Cell biology; Receptor; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003920061,0.000262882,0.0003717746,0.00008182984,0.0004621234,0.00002576817,0.0002077324,0.0003108462,0.000312873],"category_scores_gemma":[0.00004329692,0.0001830358,0.0000431725,0.0001163904,0.0002755075,0.0002376047,0.0002842745,0.0002904242,0.00006184079],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002644216,"about_ca_system_score_gemma":0.00009257043,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002570284,"about_ca_topic_score_gemma":0.0001364159,"domain_scores_codex":[0.998395,0.0004039213,0.0003997104,0.0002896095,0.00001292286,0.0004988948],"domain_scores_gemma":[0.999085,0.0003377765,0.0002115879,0.0002614444,0.00008303631,0.00002112195],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004189754,0.0001916815,0.001080547,0.00002301285,0.0002335314,1.091952e-7,0.002882322,1.440895e-7,0.9905389,0.002399968,0.0001652887,0.002065553],"study_design_scores_gemma":[0.0007802385,0.0002551242,0.04168098,0.0000116375,0.00006206983,0.0001017945,0.001268856,2.747532e-7,0.9217808,0.0004253384,0.03342837,0.0002044935],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9829422,0.01384126,0.0006448965,0.0001540704,0.00159436,0.0002795901,0.00003049211,0.00005183077,0.0004613482],"genre_scores_gemma":[0.996975,0.001000505,0.001007273,0.00004273619,0.00003986818,0.000056253,0.00002379694,0.000021549,0.0008330034],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06875804,"threshold_uncertainty_score":0.7463984,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01482848458571072,"score_gpt":0.2418197242849061,"score_spread":0.2269912396991954,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}