{"id":"W1969606058","doi":"10.1038/mi.2012.12","title":"Neisseria gonorrhoeae selectively suppresses the development of Th1 and Th2 cells, and enhances Th17 cell responses, through TGF-β-dependent mechanisms","year":2012,"lang":"en","type":"article","venue":"Mucosal Immunology","topic":"Bacterial Infections and Vaccines","field":"Immunology and Microbiology","cited_by":100,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; University at Buffalo; National Institutes of Health; John R. Oishei Foundation; Canadian Institutes of Health Research; U.S. Department of Veterans Affairs","keywords":"Neisseria gonorrhoeae; Immune system; Immunity; Acquired immune system; Immunology; Biology; Innate immune system; Microbiology; Pathogen; Transforming growth factor; Blockade; Cell biology; Receptor; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001684032,0.0003058603,0.0002285339,0.0002017403,0.00009345742,0.0002145285,0.00009843524,0.0001718774,0.0007867871],"category_scores_gemma":[0.0001897134,0.0001060552,0.000158136,0.00007998008,0.0001901987,0.0001073352,0.0001330464,0.0003928241,0.0001536069],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009452371,"about_ca_system_score_gemma":0.0002242553,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004801302,"about_ca_topic_score_gemma":0.001126117,"domain_scores_codex":[0.999833,0.00003997693,0.00001139579,0.00001569064,0.00004865464,0.00005129103],"domain_scores_gemma":[0.9998741,0.00002804171,0.00003385458,0.00001652085,0.00001852524,0.00002895703],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001725047,0.00006328988,0.0006330787,0.00005007993,0.000006410383,0.00004788117,0.00001059479,0.00001967295,0.9943679,0.00003843359,0.00003445533,0.004555674],"study_design_scores_gemma":[0.00008335764,0.002763073,0.03207875,0.0000337188,0.0000579421,0.0007023137,0.00008485746,0.0003375054,0.9578509,0.00009718255,0.005903891,0.000006609025],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931055,0.003281174,0.0008094566,0.0001126495,0.00005072073,0.00003496446,0.00007438625,0.00003569789,0.002495541],"genre_scores_gemma":[0.9952025,0.002337631,0.0007263534,0.00008627334,0.00003601817,0.00002522055,0.00008042633,0.00000655869,0.001499042],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007867871,"threshold_uncertainty_score":0.002632022,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01482848458571072,"score_gpt":0.2418197242849061,"score_spread":0.2269912396991954,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}