{"id":"W1969646890","doi":"10.1006/clim.1999.4806","title":"Activated B Cells Express Increased Levels of Costimulatory Molecules in Young Autoimmune NZB and (NZB × NZW)F1 Mice","year":2000,"lang":"en","type":"article","venue":"Clinical Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":93,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto Western Hospital; University of Toronto","funders":"","keywords":"CD40; Biology; Flow cytometry; Immunology; Population; B cell; T cell; Molecular biology; Cell biology; Immune system; Cytotoxic T cell; Antibody; In vitro; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000850116,0.0005340838,0.001544809,0.000306561,0.0001870102,0.00001609654,0.0007676276,0.00176092,0.004757748],"category_scores_gemma":[0.0003270427,0.0005123849,0.0002772122,0.0003379046,0.002724101,0.0001800207,0.0003670391,0.001627851,0.0009088098],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006069457,"about_ca_system_score_gemma":0.0001754626,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001222324,"about_ca_topic_score_gemma":0.00007522531,"domain_scores_codex":[0.9943125,0.001784946,0.001935584,0.0009462356,0.0000629106,0.0009578248],"domain_scores_gemma":[0.9966747,0.001723975,0.0004876707,0.0009206292,0.0001356766,0.00005730684],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001821515,0.001107007,0.007122783,0.00002608134,0.0006335084,0.0000392958,0.0002911256,0.00001594159,0.9724758,0.0001808929,0.000276228,0.0160098],"study_design_scores_gemma":[0.01005872,0.001055231,0.1856362,0.0001155058,0.0001494755,0.0001770802,0.0002634184,0.0000297792,0.7895688,0.0003287391,0.01197762,0.0006393967],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9852465,0.01026342,0.00002591147,0.0001750864,0.001279636,0.0004812237,0.00009170611,0.0001257406,0.002310797],"genre_scores_gemma":[0.9935713,0.002009081,0.0002232071,0.0002605258,0.00003268027,0.00003743779,0.00009074099,0.00005758317,0.003717449],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.182907,"threshold_uncertainty_score":0.9999899,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02350996767846401,"score_gpt":0.283286606294515,"score_spread":0.2597766386160509,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}