{"id":"W1969730273","doi":"10.1016/j.ydbio.2013.03.013","title":"Organizer formation in Hydra is disrupted by thalidomide treatment","year":2013,"lang":"en","type":"article","venue":"Developmental Biology","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; Ontario Institute for Cancer Research; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Canadian Institutes of Health Research","keywords":"Lernaean Hydra; Thalidomide; Biology; Wnt signaling pathway; Cell biology; Budding; Signal transduction; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001306708,0.0004451187,0.0005120077,0.0004244021,0.000391453,0.0005966875,0.0005302196,0.000574153,0.002518897],"category_scores_gemma":[0.0001491916,0.000559453,0.0004749181,0.0001879147,0.0007189271,0.0003162454,0.0007046356,0.001747786,0.0006371271],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006250726,"about_ca_system_score_gemma":0.0004657673,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004165938,"about_ca_topic_score_gemma":0.005907461,"domain_scores_codex":[0.9997328,0.00001810191,0.00002500101,0.00006874489,0.00007928986,0.00007606007],"domain_scores_gemma":[0.9996555,0.00003168328,0.0001073873,0.00003321734,0.00002022608,0.0001519694],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008621575,0.00000793497,0.0001950566,0.00001628321,0.000007283413,0.0001119617,0.00001987051,0.00003602707,0.9990423,0.0001063543,0.0000619549,0.0003086822],"study_design_scores_gemma":[0.0000242411,0.00006234712,0.01178496,0.000005562023,0.00002098537,0.0002708778,0.0000966778,0.0006617114,0.9834695,0.00006011311,0.003531301,0.00001175875],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9911907,0.001028529,0.002553137,0.000339559,0.0001631215,0.00004152085,0.001362933,0.0002768,0.003043777],"genre_scores_gemma":[0.9861836,0.0004060718,0.00150597,0.0001450648,0.00002037365,0.00005607915,0.0009509933,0.0001351437,0.01059667],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004165938,"threshold_uncertainty_score":0.008426547,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008624901625493432,"score_gpt":0.2264644307519422,"score_spread":0.2178395291264488,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}