{"id":"W1969785686","doi":"10.1097/moh.0b013e3283497f54","title":"The pathogenesis of essential thrombocythemia","year":2011,"lang":"en","type":"review","venue":"Current Opinion in Hematology","topic":"Myeloproliferative Neoplasms: Diagnosis and Treatment","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; Terry Fox Research Institute","funders":"Kay Kendall Leukaemia Fund","keywords":"Essential thrombocythemia; Biology; Pathogenesis; Genetics; Phenotype; Human genetics; Myeloproliferative Disorders; Mechanism (biology); Myelofibrosis; Bioinformatics; Polycythemia vera; Immunology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002094777,0.0004032422,0.002393859,0.0001930743,0.00006711159,0.000007096039,0.0002050875,0.0003083578,0.0001438674],"category_scores_gemma":[0.0001271069,0.0002290153,0.0005279658,0.0002594356,0.0002104622,0.00001896714,0.0001161887,0.0003541043,0.00008645483],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008630125,"about_ca_system_score_gemma":0.0004299834,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007611994,"about_ca_topic_score_gemma":0.000004235925,"domain_scores_codex":[0.9977093,0.0002600508,0.001090778,0.0004413597,0.0001675021,0.0003310549],"domain_scores_gemma":[0.998098,0.0005930788,0.0005607785,0.0005638654,0.00009514495,0.00008917012],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003743618,0.0007873958,0.002843872,0.040023,0.0003289318,0.000009260363,0.0001158877,2.32947e-8,2.432117e-7,0.04266237,0.00194507,0.9112465],"study_design_scores_gemma":[0.0005552907,0.0001303865,0.0003259366,0.02162395,0.0004343124,0.0003501866,0.00001265921,0.000001340946,0.00001994993,0.0001799899,0.9761925,0.0001734572],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00004131812,0.9945215,0.00001612796,0.00004393019,0.003805357,0.001274989,0.00003979542,0.00001731766,0.0002396405],"genre_scores_gemma":[0.00008181532,0.9985943,0.00006187112,0.000002756676,0.0002212351,0.0007904883,0.0001919171,0.00003787626,0.00001770509],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9742475,"threshold_uncertainty_score":0.9338972,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1424649438794859,"score_gpt":0.4276597470132881,"score_spread":0.2851948031338022,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}