{"id":"W1969828710","doi":"10.1016/j.ijpddr.2014.09.005","title":"Drug resistance analysis by next generation sequencing in Leishmania","year":2014,"lang":"en","type":"review","venue":"International Journal for Parasitology Drugs and Drug Resistance","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":101,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Biology; Drug resistance; Leishmania; Genetics; Computational biology; DNA sequencing; Gene; Identification (biology); Population; Single-nucleotide polymorphism; Genotype; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001802303,0.0006043682,0.002805118,0.001314388,0.0003655313,0.0003423747,0.0006486339,0.0002959766,0.00003599636],"category_scores_gemma":[0.0006946409,0.0005104923,0.0009025545,0.0006388282,0.0002649598,0.0003036499,0.0001186898,0.001081365,0.00001444201],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001559793,"about_ca_system_score_gemma":0.0006464929,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006411934,"about_ca_topic_score_gemma":0.003704605,"domain_scores_codex":[0.9952702,0.0005151285,0.001682342,0.0009196912,0.0009508711,0.0006617481],"domain_scores_gemma":[0.9963851,0.0009805171,0.001121741,0.0004026833,0.0008282817,0.0002816884],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001736251,0.0004316442,0.003961767,0.01443876,0.02066988,0.001471186,0.0024262,0.00004225519,0.000134131,0.005316922,0.671036,0.278335],"study_design_scores_gemma":[0.001187492,0.00002328349,0.00008179369,0.004055426,0.001722731,0.0001780033,0.0001595443,0.0001734889,0.00001393018,0.0003550911,0.991611,0.0004382034],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001954197,0.9903747,0.0009786426,0.003430817,0.0009921534,0.0008402253,0.0001204808,0.0000306631,0.001278082],"genre_scores_gemma":[0.00254275,0.9702972,0.001783069,0.0002701806,0.001051096,0.0002386213,0.0003834093,0.0000710657,0.02336265],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.320575,"threshold_uncertainty_score":0.9997346,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06306305574010403,"score_gpt":0.4045048958390189,"score_spread":0.3414418400989149,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}