{"id":"W1969863513","doi":"10.1038/nrg2666","title":"The expansion of newborn screening: is reproductive benefit an appropriate pursuit?","year":2009,"lang":"en","type":"review","venue":"Nature Reviews Genetics","topic":"Metabolism and Genetic Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; University of Toronto","funders":"","keywords":"Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003339617,0.001076872,0.002826859,0.001283452,0.0004519674,0.00128488,0.001748973,0.004145537,0.004999347],"category_scores_gemma":[0.005458537,0.0003126945,0.0004962306,0.001223817,0.002220777,0.002312594,0.001283609,0.006245537,0.002236205],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001317756,"about_ca_system_score_gemma":0.001836371,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001792475,"about_ca_topic_score_gemma":0.003310438,"domain_scores_codex":[0.9994154,0.0001972139,0.00006515237,0.00007271642,0.0001932313,0.00005628384],"domain_scores_gemma":[0.9968724,0.00223541,0.0001329804,0.00007113664,0.0004408619,0.0002472198],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001649775,0.00007477609,0.000386668,0.003913783,0.00008626429,0.0007202288,0.00006153793,0.000396875,0.0005431545,0.02041576,0.1605104,0.8127256],"study_design_scores_gemma":[0.00007001625,0.00008356449,0.000984641,0.004452076,0.0001025198,0.002897404,0.00009896735,0.0001314655,0.0001965766,0.01179737,0.9791535,0.0000318712],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001183208,0.9840801,0.0004757418,0.01125216,0.001990729,0.000003758667,0.00002363285,0.00001657472,0.00203897],"genre_scores_gemma":[0.001312139,0.9880285,0.0005602769,0.006554913,0.002722485,0.000009370548,0.00002637828,0.000005419065,0.0007804559],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004999347,"threshold_uncertainty_score":0.01766181,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03145139966512509,"score_gpt":0.3454081690812251,"score_spread":0.3139567694161,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}