{"id":"W1969954884","doi":"10.1016/j.molimm.2009.12.011","title":"Role of Hsp90 in CpG ODN mediated immunostimulation in avian macrophages","year":2010,"lang":"en","type":"article","venue":"Molecular Immunology","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":19,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; University of Saskatchewan","keywords":"Protein kinase B; MAPK/ERK pathway; TLR9; PI3K/AKT/mTOR pathway; Cell biology; Phosphorylation; Chemokine; Signal transduction; Biology; Hsp90; Toll-Like Receptor 9; Kinase; Nitric oxide; CpG Oligodeoxynucleotide; Chemistry; Molecular biology; Immune system; Immunology; Biochemistry; Heat shock protein; Gene expression; Endocrinology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004265031,0.0002033067,0.000399536,0.0006279213,0.000044973,0.00000699414,0.0003160266,0.0006284399,0.0005835752],"category_scores_gemma":[0.00041075,0.0002125573,0.00008816297,0.0004022383,0.0002656128,0.0001211125,0.0001108087,0.0007421927,0.0003593092],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004021617,"about_ca_system_score_gemma":0.00008911405,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006054434,"about_ca_topic_score_gemma":0.0002144764,"domain_scores_codex":[0.9981492,0.0004435305,0.0006612518,0.0002782607,0.00004253049,0.0004252467],"domain_scores_gemma":[0.9990622,0.0001800027,0.0002014817,0.0004687043,0.00007806062,0.000009563712],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000576585,0.0001374141,0.005156264,0.000007248399,0.00006876231,0.00003127039,0.000518748,0.00003272409,0.9850507,0.002339088,0.000006433452,0.00607472],"study_design_scores_gemma":[0.00204777,0.0001559619,0.2327078,0.00002484413,0.000009814552,0.0000577676,0.0001563125,0.00004610132,0.7620517,0.0007396965,0.00183737,0.0001648804],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929627,0.005065893,0.00005825454,0.0002027927,0.0004312224,0.0002990593,0.000005945526,0.00003774535,0.0009363606],"genre_scores_gemma":[0.9993525,0.00009109658,0.00007650823,0.00004970679,0.00000561686,0.00005118775,0.0002351629,0.00002346607,0.0001148069],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2275515,"threshold_uncertainty_score":0.8667837,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002487200969121737,"score_gpt":0.2084816114958777,"score_spread":0.2059944105267559,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}