{"id":"W1969954884","doi":"10.1016/j.molimm.2009.12.011","title":"Role of Hsp90 in CpG ODN mediated immunostimulation in avian macrophages","year":2010,"lang":"en","type":"article","venue":"Molecular Immunology","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":19,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; University of Saskatchewan","keywords":"Protein kinase B; MAPK/ERK pathway; TLR9; PI3K/AKT/mTOR pathway; Cell biology; Phosphorylation; Chemokine; Signal transduction; Biology; Hsp90; Toll-Like Receptor 9; Kinase; Nitric oxide; CpG Oligodeoxynucleotide; Chemistry; Molecular biology; Immune system; Immunology; Biochemistry; Heat shock protein; Gene expression; Endocrinology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009598674,0.0001820942,0.00013303,0.0001177142,0.0001338542,0.0002465053,0.000103941,0.0002251661,0.0006856678],"category_scores_gemma":[0.00005370995,0.00009040307,0.00018179,0.00005189444,0.0001478475,0.0002023989,0.0001683913,0.0003372388,0.0002760137],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001999948,"about_ca_system_score_gemma":0.0001310392,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007583625,"about_ca_topic_score_gemma":0.001220091,"domain_scores_codex":[0.9999235,0.00001187868,0.000004362086,0.00001099091,0.00001338538,0.00003585587],"domain_scores_gemma":[0.9999483,0.000004146582,0.00001446221,0.000006319975,0.000008823681,0.0000180494],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009777208,0.00001093174,0.0002635083,0.00002317941,0.000004588208,0.00004924191,0.000009981,0.00003599525,0.9982551,0.00008276439,0.00003340057,0.001133429],"study_design_scores_gemma":[0.00002384194,0.0004526687,0.05543605,0.00001708541,0.00002745552,0.0004098622,0.0001869668,0.001164135,0.9395868,0.000141513,0.002545838,0.000007806673],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941992,0.002319259,0.001344103,0.0001342626,0.00002380373,0.00001589895,0.0002239022,0.00003805011,0.00170154],"genre_scores_gemma":[0.9977223,0.0005065145,0.0004623489,0.00003576196,0.000006018107,0.000006187968,0.0001429283,0.000005100234,0.001112752],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007583625,"threshold_uncertainty_score":0.002293766,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002487200969121737,"score_gpt":0.2084816114958777,"score_spread":0.2059944105267559,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}