{"id":"W1969994359","doi":"10.3109/02656736.2014.968641","title":"Mild thermotolerance induced at 40 °C protects cells against hyperthermia-induced pro-apoptotic changes in Bcl-2 family proteins","year":2014,"lang":"en","type":"article","venue":"International Journal of Hyperthermia","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Université du Québec à Montréal","keywords":"Apoptosis; Bcl-2 family; Hyperthermia; HeLa; Cell biology; Puma; Biology; Chromatin; Caspase; Prophase; Programmed cell death; Molecular biology; Cell; Biochemistry; DNA; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001012248,0.0003287506,0.0003525046,0.0001254042,0.0001497697,0.0001959619,0.000107205,0.0002188407,0.001895763],"category_scores_gemma":[0.00009997329,0.00009811681,0.0002700648,0.0001188732,0.0002439612,0.0001808266,0.0001903071,0.0005193366,0.0002588965],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001574546,"about_ca_system_score_gemma":0.0001396201,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002207867,"about_ca_topic_score_gemma":0.0002569452,"domain_scores_codex":[0.9999104,0.00001471692,0.000006698252,0.00001951882,0.0000274649,0.00002129839],"domain_scores_gemma":[0.999923,0.000009052423,0.00002668683,0.00001317989,0.00001274102,0.00001530985],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000130376,0.00001479409,0.0001214842,0.00003468702,0.00000487871,0.0000200543,0.00001123387,0.00003373775,0.9990422,0.0000192139,0.00001815844,0.0005491394],"study_design_scores_gemma":[0.00002427333,0.001117169,0.008402582,0.00001176477,0.00002473638,0.000263734,0.00003398935,0.000287249,0.9873959,0.00007012182,0.002361385,0.000007137026],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924356,0.003890086,0.0024863,0.000121797,0.00004949102,0.0000390419,0.0001822778,0.000101786,0.0006936599],"genre_scores_gemma":[0.9964715,0.00108866,0.0008011642,0.00007927178,0.00002154881,0.00006399801,0.000294463,0.00001164288,0.00116777],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001895763,"threshold_uncertainty_score":0.006341934,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01760322277291245,"score_gpt":0.24499159222195,"score_spread":0.2273883694490376,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}