{"id":"W1970037588","doi":"10.1074/jbc.m009073200","title":"PRA Isoforms Are Targeted to Distinct Membrane Compartments","year":2001,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":78,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Rab; GTPase; Golgi apparatus; Endoplasmic reticulum; Prenylation; Cell biology; Gene isoform; Biology; Transport protein; Guanine nucleotide exchange factor; Subcellular localization; GTP-binding protein regulators; Vesicular transport protein; Biochemistry; G protein; Signal transduction; Vesicle; Cytoplasm; Membrane","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001882625,0.0001525571,0.0002429848,0.00001627663,0.00005162755,0.00001501155,0.0002241115,0.0002011973,0.0002513083],"category_scores_gemma":[0.00009553043,0.0001047328,0.0001837733,0.00008780976,0.00004450067,0.00000380179,0.00004019472,0.0001537726,0.000009065401],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001945273,"about_ca_system_score_gemma":0.0000271985,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001242698,"about_ca_topic_score_gemma":0.000001909742,"domain_scores_codex":[0.999045,0.00001859509,0.000374635,0.0001880607,0.0001534855,0.0002202973],"domain_scores_gemma":[0.9992626,0.000008287629,0.0002354346,0.0001540731,0.0001274732,0.0002121255],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004177646,0.0001282413,0.05436259,0.00001292768,0.0000437314,0.00006390335,0.000008464499,0.00002248339,0.9444327,9.783864e-7,0.0002800942,0.0002261337],"study_design_scores_gemma":[0.0007396084,0.0004041551,0.05998965,0.00003096451,0.00002131665,0.0002612295,0.00007487268,0.000007903413,0.8201951,0.00003237132,0.1180321,0.0002106311],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956112,0.0004116257,0.0027565,0.0002838708,0.00009473051,0.00006778547,0.00001479907,0.000007243184,0.0007522721],"genre_scores_gemma":[0.9979973,0.000199703,0.0002907441,0.000191123,0.0004524106,0.000002684152,0.0004807282,0.000008745699,0.0003765963],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1242375,"threshold_uncertainty_score":0.427088,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01932265045222691,"score_gpt":0.2463178646325818,"score_spread":0.2269952141803549,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}