{"id":"W1970037588","doi":"10.1074/jbc.m009073200","title":"PRA Isoforms Are Targeted to Distinct Membrane Compartments","year":2001,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":78,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Rab; GTPase; Golgi apparatus; Endoplasmic reticulum; Prenylation; Cell biology; Gene isoform; Biology; Transport protein; Guanine nucleotide exchange factor; Subcellular localization; GTP-binding protein regulators; Vesicular transport protein; Biochemistry; G protein; Signal transduction; Vesicle; Cytoplasm; Membrane","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002019821,0.0003490547,0.0003768372,0.0002566702,0.0001947131,0.0006411579,0.000286118,0.0004127916,0.002096871],"category_scores_gemma":[0.0003012662,0.0002664634,0.0004440442,0.0001849314,0.0002066618,0.0006357778,0.0004146745,0.0008170081,0.001645285],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002917383,"about_ca_system_score_gemma":0.0001701416,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002333885,"about_ca_topic_score_gemma":0.0003203957,"domain_scores_codex":[0.9997312,0.00001777602,0.00001902874,0.00009428092,0.00007101706,0.00006664899],"domain_scores_gemma":[0.9997216,0.00003875721,0.00006426597,0.00005020044,0.00006387755,0.00006126866],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008286163,0.000006858064,0.0002021518,0.00002092867,0.000003529821,0.00007181369,0.00001829752,0.00001382318,0.9984105,0.0002322596,0.0000251757,0.0009117175],"study_design_scores_gemma":[0.00004505146,0.0003421079,0.02113389,0.0000115695,0.00002988855,0.003984894,0.0001335615,0.0009892691,0.9623316,0.0004679951,0.01051274,0.00001726208],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9855736,0.001906064,0.008559262,0.0002277631,0.00006553836,0.00004367537,0.0005552385,0.0001697726,0.002899012],"genre_scores_gemma":[0.9723426,0.002318182,0.008250385,0.0002262319,0.00007947335,0.00007463218,0.00230145,0.00007789495,0.01432902],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002096871,"threshold_uncertainty_score":0.007014692,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01932265045222691,"score_gpt":0.2463178646325818,"score_spread":0.2269952141803549,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}