{"id":"W1970064993","doi":"10.1053/j.gastro.2003.09.020","title":"Colonic bacterial superantigens evoke an inflammatory response and exaggerate disease in mice recovering from colitis","year":2003,"lang":"en","type":"article","venue":"Gastroenterology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; Crohn's and Colitis Foundation of Canada; Crohn's and Colitis Foundation","keywords":"Colitis; Superantigen; Myeloperoxidase; Inflammatory bowel disease; Immunology; Inflammation; Ovalbumin; Enterotoxin; Medicine; T cell; Chemistry; Antigen; Immune system; Pathology; Disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004732853,0.00150123,0.001063536,0.001347651,0.0005310359,0.000670889,0.0003713125,0.001337633,0.002033276],"category_scores_gemma":[0.0004696614,0.0007987748,0.0008959524,0.0004153482,0.001301345,0.0008565628,0.000534116,0.004214903,0.0005954338],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004757216,"about_ca_system_score_gemma":0.0003680847,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003684911,"about_ca_topic_score_gemma":0.0008457905,"domain_scores_codex":[0.9992912,0.0001160014,0.00007275004,0.0001151896,0.000127792,0.0002770202],"domain_scores_gemma":[0.998478,0.0001239402,0.0004115584,0.0001775605,0.00005698207,0.000751955],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002172543,0.0004032626,0.0005834815,0.00005354385,0.00001342627,0.0002625596,0.00006059629,0.00009732707,0.9952251,0.0001620021,0.00007210427,0.0008940562],"study_design_scores_gemma":[0.0004964332,0.00697021,0.02963765,0.00004926102,0.0001237488,0.002186005,0.0005542565,0.001603554,0.9560462,0.0006803796,0.001596454,0.00005582835],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997332,0.0005665566,0.0006638494,0.0002969602,0.00006725649,0.0000325278,0.0002960265,0.0001190042,0.0006257225],"genre_scores_gemma":[0.9948195,0.0006040324,0.00111029,0.0002606162,0.0000616418,0.00007359651,0.0003454794,0.00009601176,0.002628977],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002033276,"threshold_uncertainty_score":0.006801963,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006459073050549897,"score_gpt":0.2249460795681601,"score_spread":0.2184870065176102,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}