{"id":"W1970072513","doi":"10.1074/jbc.m114.550111","title":"The Mitochondrial Protein NLRX1 Controls the Balance between Extrinsic and Intrinsic Apoptosis","year":2014,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":81,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Azoxymethane; Mitochondrion; Apoptosis; Cell biology; Biology; Cytosol; Cancer research; Carcinogenesis; Cancer; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001181217,0.0002317856,0.0001677594,0.0001085,0.0001409703,0.0003085124,0.0001231241,0.000211416,0.0004499931],"category_scores_gemma":[0.0001132933,0.00007242169,0.0001536979,0.00007760275,0.0002444828,0.0002498888,0.0001943441,0.0003827081,0.0001817916],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002670517,"about_ca_system_score_gemma":0.000112999,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001388946,"about_ca_topic_score_gemma":0.0002007753,"domain_scores_codex":[0.9998226,0.0000364216,0.00001715523,0.00004297026,0.00004225721,0.00003857825],"domain_scores_gemma":[0.9998626,0.00001515495,0.00006021675,0.00001387596,0.00001898087,0.00002924097],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006007269,0.000004211631,0.0003106647,0.00001555882,0.000001812793,0.00003024974,0.00001660956,0.00002870666,0.9987651,0.00009751542,0.00001381583,0.0006555919],"study_design_scores_gemma":[0.00001062841,0.000180333,0.01109935,0.000009743077,0.00001151585,0.0004464338,0.00008506322,0.0008966141,0.9848161,0.0001307268,0.002308665,0.00000488899],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940096,0.002240329,0.002873908,0.0001640034,0.00001471366,0.000007125913,0.0001269506,0.00005212751,0.0005112442],"genre_scores_gemma":[0.997268,0.0008841254,0.0008196947,0.00001999209,0.000006175254,0.000005745939,0.0001233935,0.00000662745,0.0008663124],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004499931,"threshold_uncertainty_score":0.001937628,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008751469117086257,"score_gpt":0.227724398773595,"score_spread":0.2189729296565088,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}