{"id":"W1970171004","doi":"10.1007/s00125-002-0926-2","title":"TNF-Related Apoptosis-Inducing Ligand Death Pathway-Mediated Human Beta-Cell Destruction","year":2002,"lang":"en","type":"article","venue":"Diabetologia","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Universitat Autònoma de Barcelona; Universitat de Barcelona; University of Miami; Canadian Diabetes Association; Children's Hospital Foundation; University of Minnesota; Juvenile Diabetes Research Foundation International","keywords":"Cytotoxicity; Apoptosis; Programmed cell death; Tumor necrosis factor alpha; Cytotoxic T cell; Cell biology; Cell culture; Biology; Receptor; Molecular biology; Chemistry; Cancer research; Immunology; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001442251,0.0002179135,0.0002100791,0.00007450254,0.0002156033,0.00003484116,0.0001443847,0.0004328155,0.0001172187],"category_scores_gemma":[0.00002880623,0.0001996212,0.0001136419,0.0001379672,0.00005154548,0.000007876384,0.00006644479,0.0001491652,0.00007273812],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002293662,"about_ca_system_score_gemma":0.00001258534,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001564374,"about_ca_topic_score_gemma":0.000004929603,"domain_scores_codex":[0.9987094,0.00006295937,0.0002995266,0.0004513212,0.0001306045,0.0003461738],"domain_scores_gemma":[0.9993386,0.00001184795,0.0001489712,0.0003360342,0.00006620109,0.00009832877],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000004555302,0.00008331709,0.004247617,0.00001423666,0.0000368025,0.000002569169,0.00004825335,0.00005734687,0.9905452,0.0003252851,0.0004438108,0.004191057],"study_design_scores_gemma":[0.0007413178,0.000280273,0.007045643,0.00001330722,0.00003950677,0.00000966407,0.00003527306,0.0003912353,0.9878597,0.0002783052,0.00299342,0.0003123753],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952917,0.0007912689,0.0002540204,0.00005601451,0.000349021,0.000201546,0.00001028374,0.00006603343,0.002980089],"genre_scores_gemma":[0.9972879,0.0001605686,0.0003939917,0.00007533457,0.000135925,0.00002062461,0.0004413762,0.00003203003,0.001452291],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003878681,"threshold_uncertainty_score":0.8140316,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01515674007936427,"score_gpt":0.2149572030793154,"score_spread":0.1998004629999511,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}