{"id":"W1970171004","doi":"10.1007/s00125-002-0926-2","title":"TNF-Related Apoptosis-Inducing Ligand Death Pathway-Mediated Human Beta-Cell Destruction","year":2002,"lang":"en","type":"article","venue":"Diabetologia","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Universitat Autònoma de Barcelona; Universitat de Barcelona; University of Miami; Canadian Diabetes Association; Children's Hospital Foundation; University of Minnesota; Juvenile Diabetes Research Foundation International","keywords":"Cytotoxicity; Apoptosis; Programmed cell death; Tumor necrosis factor alpha; Cytotoxic T cell; Cell biology; Cell culture; Biology; Receptor; Molecular biology; Chemistry; Cancer research; Immunology; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002086196,0.0002938378,0.0001556047,0.0002502221,0.0001477852,0.0002949732,0.0001532115,0.0001604225,0.001409678],"category_scores_gemma":[0.0001450291,0.0001100093,0.0001625976,0.0001619247,0.0001589721,0.0001763349,0.0001848863,0.0003840299,0.0004052474],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000348425,"about_ca_system_score_gemma":0.0001407877,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003900171,"about_ca_topic_score_gemma":0.0002555392,"domain_scores_codex":[0.999898,0.00002724407,0.000008835633,0.00001147162,0.00001595109,0.00003850195],"domain_scores_gemma":[0.9999154,0.00002513555,0.00001500506,0.0000225747,0.000008174253,0.00001372683],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001233506,0.00008490788,0.000947392,0.00009738682,0.00001451182,0.0004187718,0.00005372721,0.0002330803,0.9895896,0.0006946505,0.0001788321,0.006453617],"study_design_scores_gemma":[0.0001584916,0.0006064533,0.01383371,0.0000141816,0.00003282174,0.002500626,0.00004864868,0.001221951,0.9774011,0.0003659244,0.003809553,0.000006454661],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9883878,0.004233074,0.002537361,0.00008745871,0.00004005545,0.00003738075,0.0004302316,0.00009306158,0.004153736],"genre_scores_gemma":[0.9959313,0.001098119,0.0005497015,0.00003643963,0.000008436086,0.0000230699,0.0004603633,0.000008306405,0.00188417],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001409678,"threshold_uncertainty_score":0.00471586,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01515674007936427,"score_gpt":0.2149572030793154,"score_spread":0.1998004629999511,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}