{"id":"W1970248850","doi":"10.1016/j.immuni.2010.08.015","title":"Integrin-Induced PIP5K1C Kinase Polarization Regulates Neutrophil Polarization, Directionality, and In Vivo Infiltration","year":2010,"lang":"en","type":"article","venue":"Immunity","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":79,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"National Center for Research Resources; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Institute on Drug Abuse; National Institutes of Health; National Cancer Institute; National Heart, Lung, and Blood Institute","keywords":"Directionality; Biology; In vivo; Polarization (electrochemistry); Integrin; Cell biology; Infiltration (HVAC); Kinase; Molecular biology; Biochemistry; Chemistry; Genetics; Cell; Materials science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004875223,0.0001363519,0.0001834995,0.0003219824,0.0001648869,0.00006123323,0.00009662028,0.0001909436,0.0003088423],"category_scores_gemma":[0.0009032585,0.0001321848,0.00003660447,0.0005699828,0.0001011291,0.0002112153,0.0001051433,0.0008456328,0.00001345908],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006801733,"about_ca_system_score_gemma":0.000144101,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002678354,"about_ca_topic_score_gemma":0.001197143,"domain_scores_codex":[0.9987993,0.0001779454,0.0002938354,0.0002239745,0.0003054366,0.0001995545],"domain_scores_gemma":[0.9990019,0.0001121524,0.00006952755,0.0003920528,0.0002942212,0.0001301757],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001067455,0.0001654779,0.1767677,0.00002980693,0.000008582903,0.000006347215,0.0001241596,0.000001659677,0.8204407,0.0005523032,0.00002676103,0.001769765],"study_design_scores_gemma":[0.0006587835,0.0000821642,0.6848692,0.00002856206,0.00001071601,0.00004011044,0.0000502785,0.0004276095,0.312831,0.00039057,0.0005180173,0.00009304721],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966545,0.00003872243,0.00007658628,0.001132701,0.0001438316,0.0003711474,0.00000607093,0.00006299173,0.001513457],"genre_scores_gemma":[0.9983059,0.00001657118,0.0004017254,0.0001471987,0.00007687988,0.00001347017,0.0001043693,0.00002196508,0.0009119165],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5081015,"threshold_uncertainty_score":0.5390339,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01923203457236433,"score_gpt":0.2973344636374767,"score_spread":0.2781024290651124,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}