{"id":"W1970250905","doi":"10.1126/science.1150021","title":"The Chemical Genomic Portrait of Yeast: Uncovering a Phenotype for All Genes","year":2008,"lang":"en","type":"article","venue":"Science","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1046,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Mount Sinai Hospital","funders":"National Institute of General Medical Sciences","keywords":"Phenotype; Genetics; Gene; Biology; Genome; Yeast; Genotype; Strain (injury); Genotype-phenotype distinction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002426652,0.00005120424,0.00004950457,0.00001579171,0.000142169,0.00001110862,0.0003843412,0.0000279995,0.000002429454],"category_scores_gemma":[0.00009345646,0.00003626228,0.00004109401,0.00009602201,0.0005446681,0.00000200395,0.0001516086,0.00002939086,0.000003571891],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009298878,"about_ca_system_score_gemma":0.0002620098,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000086154,"about_ca_topic_score_gemma":0.000009633154,"domain_scores_codex":[0.9992983,0.000005750119,0.00009466248,0.0001928025,0.0001753574,0.0002331079],"domain_scores_gemma":[0.9995887,0.000009910209,0.00002924377,0.0002028688,0.0001097894,0.00005950726],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003405502,0.00000979186,0.0004493995,0.000004644536,0.000004583995,3.205229e-7,0.00002776989,0.00005242251,0.9965693,0.00004418541,0.0001049456,0.00269859],"study_design_scores_gemma":[0.0001176876,0.00008603497,0.003557725,0.000001704358,0.000001737782,0.000009620467,0.00001760181,0.0001805641,0.9769549,0.0001174387,0.01890062,0.0000543573],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997937,0.001087927,0.0002807768,0.00005854522,0.00007708851,0.0001048673,0.00001033068,0.000002254893,0.0004411635],"genre_scores_gemma":[0.9981995,0.0002244013,0.001133685,0.00003552346,0.00009002359,0.00001070064,0.00000384221,0.000005502739,0.0002968271],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01961439,"threshold_uncertainty_score":0.2006852,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0219077037311415,"score_gpt":0.284927942254647,"score_spread":0.2630202385235055,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}