{"id":"W1970250905","doi":"10.1126/science.1150021","title":"The Chemical Genomic Portrait of Yeast: Uncovering a Phenotype for All Genes","year":2008,"lang":"en","type":"article","venue":"Science","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1046,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Mount Sinai Hospital","funders":"National Institute of General Medical Sciences","keywords":"Phenotype; Genetics; Gene; Biology; Genome; Yeast; Genotype; Strain (injury); Genotype-phenotype distinction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009347043,0.0003795305,0.0002841409,0.0005408917,0.0002458676,0.0003271355,0.0002338092,0.0002635108,0.001134127],"category_scores_gemma":[0.0001471126,0.0001881841,0.000245123,0.0004101631,0.0003703718,0.000253746,0.0003418027,0.0005676886,0.0005943508],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001832051,"about_ca_system_score_gemma":0.0001741877,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005449911,"about_ca_topic_score_gemma":0.001258096,"domain_scores_codex":[0.9999183,0.000006821955,0.000005461995,0.00002550687,0.00003597166,0.000007873753],"domain_scores_gemma":[0.9998674,0.00002430655,0.00003330287,0.00002827591,0.00002357892,0.00002307341],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002173229,0.000002424843,0.0004399717,0.00002649471,0.000004093439,0.00005184098,0.00001009523,0.0001208631,0.9975056,0.0001523857,0.00003701849,0.001627548],"study_design_scores_gemma":[0.00000628042,0.00009048226,0.01543191,0.00001053319,0.00004833924,0.001377959,0.00006202632,0.001056506,0.9728128,0.0005691671,0.008522645,0.0000112543],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9397735,0.003000545,0.04479948,0.0005720535,0.00006011068,0.00004207883,0.005905019,0.0005965524,0.005250625],"genre_scores_gemma":[0.9579825,0.003312472,0.02827356,0.0003400971,0.00002247582,0.0000514295,0.005145921,0.0002316453,0.004639864],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001134127,"threshold_uncertainty_score":0.003794014,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0219077037311415,"score_gpt":0.284927942254647,"score_spread":0.2630202385235055,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}