{"id":"W1970254108","doi":"10.1016/j.immuni.2008.07.016","title":"Fas Receptor Expression in Germinal-Center B Cells Is Essential for T and B Lymphocyte Homeostasis","year":2008,"lang":"en","type":"article","venue":"Immunity","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":210,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph; University Health Network; University of Toronto; Ontario Institute for Cancer Research","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Leukemia and Lymphoma Society; Canadian Institutes of Health Research; Terry Fox Foundation; Deutsche Forschungsgemeinschaft","keywords":"Germinal center; Biology; B cell; Somatic hypermutation; Naive B cell; Cell biology; CD80; CD40; Molecular biology; B-1 cell; T cell; B-cell receptor; Immunology; Cytotoxic T cell; Immune system; Antibody; Antigen-presenting cell; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001934264,0.0002443171,0.000387955,0.0001648685,0.0004446067,0.00001200088,0.0002712188,0.0004080228,0.0007501275],"category_scores_gemma":[0.0000299528,0.0002223643,0.0001138157,0.000110107,0.0004609339,0.0001312034,0.0002302067,0.0003543079,0.0003269125],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006201689,"about_ca_system_score_gemma":0.00007036842,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004930999,"about_ca_topic_score_gemma":0.00003847459,"domain_scores_codex":[0.9984987,0.0002754887,0.0003601667,0.000340013,0.00003159089,0.0004939829],"domain_scores_gemma":[0.9991828,0.0001922661,0.000126692,0.000410643,0.00006028256,0.0000272755],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006319404,0.0004052336,0.001225653,0.00002883126,0.00005276003,0.00000757003,0.001593413,2.681697e-7,0.9834718,0.000011458,0.005945723,0.006625333],"study_design_scores_gemma":[0.00431472,0.0001805874,0.001141676,0.00004109569,0.00001567278,0.0001158387,0.0002642517,0.000001916472,0.8850456,0.00004522886,0.108599,0.0002343291],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907224,0.007293222,0.0001052178,0.0001435522,0.0009610155,0.0003426538,0.000125931,0.00005202138,0.0002540177],"genre_scores_gemma":[0.9922575,0.003340173,0.0002949345,0.0002134978,0.00003257026,0.00005470741,0.0001735608,0.00002531674,0.003607785],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1026533,"threshold_uncertainty_score":0.9067751,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01634008049014599,"score_gpt":0.2408476530788413,"score_spread":0.2245075725886953,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}